Name: Interfaces elétricas e optoeletrônicas bidirecionais em corações de ratos ex vivo saudáveis e isquêmicos (Vídeo) | JoVE Journal
Uploaded: 2025-07-18T13:20:00.000+00:00
Duration: 8 min 33 s
Description: Explore interfaces ópticas e elétricas bidirecionais em corações de ratos ex vivo saudáveis e isquêmicos usando eletrodos de carbono nanoporo e membranas optoeletrônicas. Este método avança a pesquisa em bioeletrônica cardíaca.

ai_agent_IP

ai_agent

maintenance

instantTrialDurationMinutes

isBiopharma

enableNewMyJoveSectionDesign

educationFeatures

seoMetaApi

ai_copilot_institution_blacklist

ai_chat_institution_blacklist

freeAccessWindow

ssoRoleCapture

scheduledMaintenanceBanner

joveLabsFeatures

disable_autoplay_for_bots

extended_trial_duration

5 minutes

<ol><li>Sunwoo, S. H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Soft+bioelectronics+for+the+management+of+cardiovascular+diseases%5BTitle%5D)+AND+%22Nat+Rev+Bioeng%22%5BJournal%5D)">Soft bioelectronics for the management of cardiovascular diseases.</a> Nat Rev Bioeng. 2 (1), 8-24 (2024).</li>
<li>Choi, H., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Adhesive+bioelectronics+for+sutureless+epicardial+interfacing%5BTitle%5D)+AND+%22Nat+Elect%22%5BJournal%5D)">Adhesive bioelectronics for sutureless epicardial interfacing.</a> Nat Elect. 6 (10), 779-789 (2023).</li>
<li>Choi, Y. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Fully+implantable+and+bioresorbable+cardiac+pacemakers+without+leads+or+batteries%5BTitle%5D)+AND+%22Nat+Biotech%22%5BJournal%5D)">Fully implantable and bioresorbable cardiac pacemakers without leads or batteries.</a> Nat Biotech. 39 (10), 1228-1238 (2021).</li>
<li>Cingolani, E., Goldhaber, J. I., Marbán, E. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Next-generation+pacemakers%3A+from+small+devices+to+biological+pacemakers%5BTitle%5D)+AND+%22Nat+Rev+Cardiol%22%5BJournal%5D)">Next-generation pacemakers: from small devices to biological pacemakers.</a> Nat Rev Cardiol. 15 (3), 139-150 (2018).</li>
<li>Sala, L., Ward-van Oostwaard, D., Tertoolen, L. G. J., Mummery, C. L., Bellin, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Electrophysiological+Analysis+of+human+Pluripotent+Stem+Cell-derived+Cardiomyocytes+%28hPSC-CMs%29+Using+Multi-electrode+Arrays+%28MEAs%29%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Electrophysiological Analysis of human Pluripotent Stem Cell-derived Cardiomyocytes (hPSC-CMs) Using Multi-electrode Arrays (MEAs).</a> J Vis Exp. (123), e55587(2017).</li>
<li>Fiegle, D. J., Volk, T., Seidel, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Isolation+of+Human+Ventricular+Cardiomyocytes+from+Vibratome-Cut+Myocardial+Slices%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Isolation of Human Ventricular Cardiomyocytes from Vibratome-Cut Myocardial Slices.</a> J Vis Exp. (159), e61167(2020).</li>
<li>Alam, P., Maliken, B. D., Ivey, M. J., Jones, S. M., Kanisicak, O. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Isolation%2C+Transfection%2C+and+Long-Term+Culture+of+Adult+Mouse+and+Rat+Cardiomyocytes%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Isolation, Transfection, and Long-Term Culture of Adult Mouse and Rat Cardiomyocytes.</a> J Vis Exp. (164), e61073(2020).</li>
<li>Nippert, F., Schreckenberg, R., Schlüter, K. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Isolation+and+Cultivation+of+Adult+Rat+Cardiomyocytes%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Isolation and Cultivation of Adult Rat Cardiomyocytes.</a> J Vis Exp. (128), e56634(2017).</li>
<li>Trayanova, N. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Whole-Heart+Modeling%3A+Applications+to+Cardiac+Electrophysiology+and+Electromechanics%5BTitle%5D)+AND+%22Circ+Res%22%5BJournal%5D)">Whole-Heart Modeling: Applications to Cardiac Electrophysiology and Electromechanics.</a> Circ Res. 108 (1), 113-128 (2011).</li>
<li>Yin, R. T., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Open+thoracic+surgical+implantation+of+cardiac+pacemakers+in+rats%5BTitle%5D)+AND+%22Nat+Protoc%22%5BJournal%5D)">Open thoracic surgical implantation of cardiac pacemakers in rats.</a> Nat Protoc. 18 (2), 374-395 (2023).</li>
<li>Wu, K., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Modifications+of+the+Langendorff+Method+for+Simultaneous+Isolation+of+Atrial+and+Ventricular+Myocytes+from+Adult+Mice%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Modifications of the Langendorff Method for Simultaneous Isolation of Atrial and Ventricular Myocytes from Adult Mice.</a> J Vis Exp. (171), e62514(2021).</li>
<li>Pendexter, C. A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Modified+Langendorff+Perfusion+for+Extended+Perfusion+Times+of+Rodent+Cardiac+Grafts%5BTitle%5D)+AND+%22J+Vis+Exp%22%5BJournal%5D)">Modified Langendorff Perfusion for Extended Perfusion Times of Rodent Cardiac Grafts.</a> J Vis Exp. (208), e66815(2024).</li>
<li>Kałużna, E., Nadel, A., Zimna, A., Rozwadowska, N., Kolanowski, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Modeling+the+human+heart+ex+vivo-current+possibilities+and+strive+for+future+applications%5BTitle%5D)+AND+%22J+Tissue+Eng+Regenerat+Med%22%5BJournal%5D)">Modeling the human heart ex vivo-current possibilities and strive for future applications.</a> J Tissue Eng Regenerat Med. 16 (10), 853-874 (2022).</li>
<li>Jiang, Y. W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Topological+supramolecular+network+enabled+high-conductivity%2C+stretchable+organic+bioelectronics%5BTitle%5D)+AND+%22Science%22%5BJournal%5D)">Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics.</a> Science. 375 (6587), 1411-1417 (2022).</li>
<li>Driscoll, N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((MXene-infused+bioelectronic+interfaces+for+multiscale+electrophysiology+and+stimulation%5BTitle%5D)+AND+%22Sci+Transl+Med%22%5BJournal%5D)">MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation.</a> Sci Transl Med. 13 (612), eabf8629(2021).</li>
<li>Gablech, I., Głowacki, E. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((State-of-the-Art+Electronic+Materials+for+Thin+Films+in+Bioelectronics%5BTitle%5D)+AND+%22Adv+Elect+Mater%22%5BJournal%5D)">State-of-the-Art Electronic Materials for Thin Films in Bioelectronics.</a> Adv Elect Mater. 9 (8), 2300258(2023).</li>
<li>Cho, Y. H., Park, Y., Kim, S., Park, J. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((3D+Electrodes+for+Bioelectronics%5BTitle%5D)+AND+%22Adv+Mater%22%5BJournal%5D)">3D Electrodes for Bioelectronics.</a> Adv Mater. 33 (47), 2005805(2021).</li>
<li>Chen, Z., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((bioresorbable%2C+transparent+microelectrode+arrays+for+multimodal+spatiotemporal+mapping+and+modulation+of+cardiac+physiology%5BTitle%5D)+AND+%22Sci+Adv%22%5BJournal%5D)">bioresorbable, transparent microelectrode arrays for multimodal spatiotemporal mapping and modulation of cardiac physiology.</a> Sci Adv. 9 (27), eadi0757(2023).</li>
<li>Jiang, Y. W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Rational+design+of+silicon+structures+for+optically+controlled+multiscale+biointerfaces%5BTitle%5D)+AND+%22Nat+Biomed+Eng%22%5BJournal%5D)">Rational design of silicon structures for optically controlled multiscale biointerfaces.</a> Nat Biomed Eng. 2 (7), 508-521 (2018).</li>
<li>Prominski, A., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Porosity-based+heterojunctions+enable+leadless+optoelectronic+modulation+of+tissues%5BTitle%5D)+AND+%22Nat+Mater%22%5BJournal%5D)">Porosity-based heterojunctions enable leadless optoelectronic modulation of tissues.</a> Nat Mater. 21 (6), 647-655 (2022).</li>
<li>Huang, Y. X., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Bioresorbable+thin-film+silicon+diodes+for+the+optoelectronic+excitation+and+inhibition+of+neural+activities%5BTitle%5D)+AND+%22Nat+Biomed+Eng%22%5BJournal%5D)">Bioresorbable thin-film silicon diodes for the optoelectronic excitation and inhibition of neural activities.</a> Nat Biomed Eng. 7 (4), 486-498 (2023).</li>
<li>Balamur, R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Capacitive+and+Efficient+Near-Infrared+Stimulation+of+Neurons+via+an+Ultrathin+AgBiS2+Nanocrystal+Layer%5BTitle%5D)+AND+%22ACS+Appl+Mater+Inter%22%5BJournal%5D)">Capacitive and Efficient Near-Infrared Stimulation of Neurons via an Ultrathin AgBiS2 Nanocrystal Layer.</a> ACS Appl Mater Inter. 16 (23), 29610-29620 (2024).</li>
<li>Karatum, O., Kaleli, H. N., Eren, G. O., Sahin, A., Nizamoglu, S. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Electrical+Stimulation+of+Neurons+with+Quantum+Dots+via+Near-Infrared+Light%5BTitle%5D)+AND+%22ACS+Nano%22%5BJournal%5D)">Electrical Stimulation of Neurons with Quantum Dots via Near-Infrared Light.</a> ACS Nano. 16 (5), 8233-8243 (2022).</li>
<li>Han, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Photovoltaic+neurointerface+based+on+aluminum+antimonide+nanocrystals%5BTitle%5D)+AND+%22Comm+Mater%22%5BJournal%5D)">Photovoltaic neurointerface based on aluminum antimonide nanocrystals.</a> Comm Mater. 2 (1), (2021).</li>
<li>Ejneby, M. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Chronic+electrical+stimulation+of+peripheral+nerves+via+deep-red+light+transduced+by+an+implanted+organic+photocapacitor%5BTitle%5D)+AND+%22Nat+Biomed+Eng%22%5BJournal%5D)">Chronic electrical stimulation of peripheral nerves via deep-red light transduced by an implanted organic photocapacitor.</a> Nat Biomed Eng. 6 (6), 741-753 (2022).</li>
<li>Li, P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Monolithic+silicon+for+high+spatiotemporal+translational+photostimulation%5BTitle%5D)+AND+%22Nature%22%5BJournal%5D)">Monolithic silicon for high spatiotemporal translational photostimulation.</a> Nature. 626 (8001), 990-998 (2024).</li>
<li>Yang, C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+bioinspired+permeable+junction+approach+for+sustainable+device+microfabrication%5BTitle%5D)+AND+%22Nat+Sustain%22%5BJournal%5D)">A bioinspired permeable junction approach for sustainable device microfabrication.</a> Nat Sustain. 7 (9), 1190-1203 (2024).</li>
<li>Shi, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Monolithic-to-focal+evolving+biointerfaces+in+tissue+regeneration+and+bioelectronics%5BTitle%5D)+AND+%22Nat+Chem+Eng%22%5BJournal%5D)">Monolithic-to-focal evolving biointerfaces in tissue regeneration and bioelectronics.</a> Nat Chem Eng. 1 (1), 73-86 (2024).</li>
<li>Shi, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Active+biointegrated+living+electronics+for+managing+inflammation%5BTitle%5D)+AND+%22Science%22%5BJournal%5D)">Active biointegrated living electronics for managing inflammation.</a> Science. 384 (6699), 1023-1030 (2024).</li>
<li>Zhang, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Marangoni+Effect-Driven+Motion+of+Miniature+Robots+and+Generation+of+Electricity+on+Water%5BTitle%5D)+AND+%22Langmuir%22%5BJournal%5D)">Marangoni Effect-Driven Motion of Miniature Robots and Generation of Electricity on Water.</a> Langmuir. 33 (44), 12609-12615 (2017).</li>
<li>Cogan, S. F. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Neural+Stimulation+and+Recording+Electrodes%5BTitle%5D)+AND+%22Ann+Rev+Biomed+Eng%22%5BJournal%5D)">Neural Stimulation and Recording Electrodes.</a> Ann Rev Biomed Eng. 10 (1), 275-309 (2008).</li>
<li>Nussinovitch, U., Gepstein, L. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Optogenetics+for+in+vivo+cardiac+pacing+and+resynchronization+therapies%5BTitle%5D)+AND+%22Nat+Biotechnol%22%5BJournal%5D)">Optogenetics for in vivo cardiac pacing and resynchronization therapies.</a> Nat Biotechnol. 33 (7), 750-754 (2015).</li>
<li>Hsueh, B., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Cardiogenic+control+of+affective+behavioural+state%5BTitle%5D)+AND+%22Nature%22%5BJournal%5D)">Cardiogenic control of affective behavioural state.</a> Nature. 615 (7951), 292-299 (2023).</li>
<li>Tian, B. Z., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Macroporous+nanowire+nanoelectronic+scaffolds+for+synthetic+tissues%5BTitle%5D)+AND+%22Nat+Mater%22%5BJournal%5D)">Macroporous nanowire nanoelectronic scaffolds for synthetic tissues.</a> Nat Mater. 11 (11), 986-994 (2012).</li>
<li>Fang, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Micelle-enabled+self-assembly+of+porous+and+monolithic+carbon+membranes+for+bioelectronic+interfaces%5BTitle%5D)+AND+%22Nat+Nanotechnol%22%5BJournal%5D)">Micelle-enabled self-assembly of porous and monolithic carbon membranes for bioelectronic interfaces.</a> Nat Nanotechnol. 16 (2), 206-213 (2021).</li>
<li>Kay, G. N., Shepard, R. B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Stimulation+and+Excitation+of+Cardiac+Tissues%5BTitle%5D)+AND+%22Clin+Cardiac+Pacing+Defibrillat+Resynchronizat+Ther%22%5BJournal%5D)">Stimulation and Excitation of Cardiac Tissues.</a> Clin Cardiac Pacing Defibrillat Resynchronizat Ther. , 61-113 (2017).</li>
<li>Zhang, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Gold-modified+nanoporous+silicon+for+photoelectrochemical+regulation+of+intracellular+condensates%5BTitle%5D)+AND+%22Nat+Nanotechnol%22%5BJournal%5D)">Gold-modified nanoporous silicon for photoelectrochemical regulation of intracellular condensates.</a> Nat Nanotechnol. , (2025).</li>
<li>Li, P., Kim, S., Tian, B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Beyond+25+years+of+biomedical+innovation+in+nano-bioelectronics%5BTitle%5D)+AND+%22Device%22%5BJournal%5D)">Beyond 25 years of biomedical innovation in nano-bioelectronics.</a> Device. 2 (7), 100401(2024).</li>
<li>Yang, C., Cheng, Z., Li, P., Tian, B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Exploring+Present+and+Future+Directions+in+Nano-Enhanced+Optoelectronic+Neuromodulation%5BTitle%5D)+AND+%22Acc+Chem+Res%22%5BJournal%5D)">Exploring Present and Future Directions in Nano-Enhanced Optoelectronic Neuromodulation.</a> Acc Chem Res. 57 (9), 1398-1410 (2024).</li>
<li>Prominski, A., Li, P., Miao, B. A., Tian, B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Nanoenabled+Bioelectrical+Modulation%5BTitle%5D)+AND+%22Acc+Mater+Res%22%5BJournal%5D)">Nanoenabled Bioelectrical Modulation.</a> Acc Mater Res. 2 (10), 895-906 (2021).</li>
<li>Li, P., Kim, S., Tian, B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Nanoenabled+Trainable+Systems%3A+From+Biointerfaces+to+Biomimetics%5BTitle%5D)+AND+%22ACS+Nano%22%5BJournal%5D)">Nanoenabled Trainable Systems: From Biointerfaces to Biomimetics.</a> ACS Nano. 16 (12), 19651-19664 (2022).</li>
<li>Majmudar, A., Kim, S., Li, P., Tian, B. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Perspectives+on+non-genetic+optoelectronic+modulation+biointerfaces+for+advancing+healthcare%5BTitle%5D)+AND+%22Med-X%22%5BJournal%5D)">Perspectives on non-genetic optoelectronic modulation biointerfaces for advancing healthcare.</a> Med-X. 2 (1), 18(2024).</li>
<li>Hwang, S. W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+Physically+Transient+Form+of+Silicon+Electronics%5BTitle%5D)+AND+%22Science%22%5BJournal%5D)">A Physically Transient Form of Silicon Electronics.</a> Science. 337 (6102), 1640-1644 (2012).</li>
<li>Yu, Y., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Enhanced+photoelectrochemical+efficiency+and+stability+using+a+conformal+TiO2+film+on+a+black+silicon+photoanode%5BTitle%5D)+AND+%22Nat+Ener%22%5BJournal%5D)">Enhanced photoelectrochemical efficiency and stability using a conformal TiO2 film on a black silicon photoanode.</a> Nat Ener. 2 (6), 17045(2017).</li>
<li>Kosta, S., Dauby, P. C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Frank-Starling+mechanism%2C+fluid+responsiveness%2C+and+length-dependent+activation%3A+Unravelling+the+multiscale+behaviors+with+an+in+silico+analysis%5BTitle%5D)+AND+%22PLoS+Computat+Bio%22%5BJournal%5D)">Frank-Starling mechanism, fluid responsiveness, and length-dependent activation: Unravelling the multiscale behaviors with an in silico analysis.</a> PLoS Computat Bio. 17 (10), e1009469(2021).</li>
<li>Silverman, D. N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Heart+Rate-Induced+Myocardial+Ca2%2B+Retention+and+Left+Ventricular+Volume+Loss+in+Patients+With+Heart+Failure+With+Preserved+Ejection+Fraction%5BTitle%5D)+AND+%22J+Am+Heart+Assoc%22%5BJournal%5D)">Heart Rate-Induced Myocardial Ca2+ Retention and Left Ventricular Volume Loss in Patients With Heart Failure With Preserved Ejection Fraction.</a> J Am Heart Assoc. 9 (17), e017215(2020).</li>
<li>Zeng, M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Printing+thermoelectric+inks+toward+next-generation+energy+and+thermal+devices%5BTitle%5D)+AND+%22Chem+Soc+Rev%22%5BJournal%5D)">Printing thermoelectric inks toward next-generation energy and thermal devices.</a> Chem Soc Rev. 51 (2), 485-512 (2022).</li>
<li>Rastogi, S. K., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Remote+nongenetic+optical+modulation+of+neuronal+activity+using+fuzzy+graphene%5BTitle%5D)+AND+%22Proc+Natl+Acad+Sci%22%5BJournal%5D)">Remote nongenetic optical modulation of neuronal activity using fuzzy graphene.</a> Proc Natl Acad Sci. 117 (24), 13339-13349 (2020).</li>
</ol>

<table><tbody><tr><td>Headstage de 16 canais</td><td>Intan Technologies</td><td>C3334</td><td></td></tr><tr><td>Cloreto de 2,3,5-trifeniltetrazólio</td><td>Sigma Aldrich</td><td>T8877-5G</td><td>cloreto de trifeniltetrazólio </td></tr><tr><td>2-propanol (IPA) </td><td>Fischer Scientific</td><td>Resposta 451-4</td><td></td></tr><tr><td>Laser de 635 nm, 500 mW</td><td>Brilho a laser</td><td>NA</td><td></td></tr><tr><td>Acetona</td><td>Fischer Scientific</td><td>A18-4</td><td></td></tr><tr><td>Evaporador de feixe eletrônico Angstrom Evovac</td><td>Angstrom</td><td>NA</td><td></td></tr><tr><td>Desenvolvedor AZ 300MIF</td><td>Microquímicos</td><td>18441123163</td><td>Revelador</td></tr><tr><td>AZ nlof 2020 </td><td>Microquímicos</td><td>1A002020</td><td></td></tr><tr><td>AZ NMP </td><td>Microquímicos</td><td>NA</td><td>Removedor de fotorresistência</td></tr><tr><td>AZ40XT-11D </td><td>Microquímicos</td><td>1000300</td><td>Fotorresistente</td></tr><tr><td>HF tamponado</td><td>Thermo Científico</td><td>AA44627K2</td><td></td></tr><tr><td>CaCl2.2H2O</td><td>Sigma Aldrich</td><td>(C3881)</td><td></td></tr><tr><td>Laser de CO2 </td><td>Sistemas Laser Universais</td><td>VLS 4.60</td><td></td></tr><tr><td>Tinta prateada condutora</td><td>PELCO</td><td>16062</td><td>Adesão condutiva entre o eletrodo e o fio de conexão do</td></tr><tr><td>Fio de cobre encapsulado 0,1 mm</td><td>Amazona</td><td>https://www.amazon.com/Enameled-Temperature-Resistance-Transformers-Inductors/dp/ B09TNM51S5/ref=asc_df_B09 TNM51S5?mcid=155de761ea4 c389ea86d45ba61a83e8d& tag =hyprod-20& linkCode=df0& hvadid =693675076770& hvpos = & hvnetw =g& hvrand=664358781094905 4431& hvpone=& hvptwo=& hvqmt =& hvdev=c& hvdvcmdl=& hvlocint =& hvlocphy=9021716& hvtargid= pla-1878323158943& PSC = 1</td><td></td></tr><tr><td>Digitalizador Digidata 1550</td><td>Dispositivos Moleculares</td><td>NA</td><td></td></tr><tr><td>Glicose</td><td>Sigma Aldrich</td><td>G7021</td><td></td></tr><tr><td>HBSS, sem cálcio, sem magnésio, sem vermelho de fenol</td><td>Thermo Científico</td><td>14175095</td><td></td></tr><tr><td>Heidelberg MLA150 escritor direto</td><td>Heidelberg</td><td>NA</td><td></td></tr><tr><td>heparina (1000 UI/kg)</td><td>Sagent Farmacêutica</td><td>1009655</td><td></td></tr><tr><td>HEPES</td><td>Sigma Aldrich</td><td>(H4034)</td><td></td></tr><tr><td>Hexano </td><td>Sigma Aldrich</td><td>Rolamento 52750-10ML</td><td>Solvente</td></tr><tr><td>HF</td><td>Fisher Científico</td><td>A513-500</td><td>Grau de traço metálico</td></tr><tr><td>Forno HMDS Vapor Prime</td><td>Sistemas de Engenharia de Rendimento</td><td>NA</td><td></td></tr><tr><td>HNO3</td><td>Fisher Científico</td><td>A509P500</td><td>Grau de traço metálico</td></tr><tr><td>Laminador a quente</td><td>Depósito de Escritório</td><td>L410-A</td><td>Encapsulamento multicamada </td></tr><tr><td>Sistemas Intan RHD</td><td>Intan Technologies</td><td>C3100</td><td></td></tr><tr><td>ECG iWorx</td><td>iWorx</td><td> IA-400D</td><td></td></tr><tr><td>Sonda iWorx LVD</td><td>iWorx</td><td>BP-100</td><td></td></tr><tr><td>Pré-amplificador iWorx</td><td>iWorx</td><td>C-ISO-256</td><td></td></tr><tr><td>Kcl</td><td>Sigma Aldrich</td><td>(Pág. 4504)</td><td></td></tr><tr><td>Balão de látex (tamanho 4)</td><td>Radnoti</td><td>170404</td><td></td></tr><tr><td>MgCl2.7H2O</td><td>Sigma Aldrich</td><td>(M9272)</td><td></td></tr><tr><td>NaCl</td><td>Sigma Aldrich</td><td>(S9625)</td><td></td></tr><tr><td>Solução contendo Nafion 117</td><td>Sigma Aldrich</td><td>31175-20-9</td><td>Reagente de fixação para padrão de carbono nanoporoso</td></tr><tr><td>NaH2PO4</td><td>Sigma Aldrich</td><td>(S0751)</td><td></td></tr><tr><td>NaOH</td><td>Sigma Aldrich</td><td>221465</td><td></td></tr><tr><td>PDMS</td><td>Fisher Científico</td><td>NC9285739</td><td></td></tr><tr><td>Plasma Therm indutivamente acoplado plasma fluoreto gravura</td><td>Plasma-Therm</td><td>NA</td><td></td></tr><tr><td>PMMA (495 A6) </td><td>Microquímicos</td><td>M130006 </td><td></td></tr><tr><td>Poli (dianidrido-co-4,4'-oxidianilina piromelítica)</td><td>Sigma Aldrich</td><td>575801</td><td>Precursor PI</td></tr><tr><td>Poli (etileno-co-acetato de vinila)</td><td>Sigma Aldrich</td><td>Rolamento 437247-250G</td><td>Polímero para infiltração</td></tr><tr><td>Poli (álcool vinílico)</td><td>Sigma Aldrich</td><td>341584-25G</td><td></td></tr><tr><td>Polietileno tereftalato (PET)</td><td>Amazona</td><td>KS-6304-21-11</td><td>Folha de PET Tipo D Transparente .0005" Espessura x 27" Largura x 10 Ft Comprimento 1 pc</td></tr><tr><td>Potenciostato</td><td>Biológico</td><td>SP-200</td><td>Estimulação elétrica</td></tr><tr><td>resistir ao forno</td><td> Despachar</td><td>LCC1-15-5</td><td></td></tr><tr><td>Microscopia eletrônica de varredura</td><td>Carl Zeiss</td><td>Esmerilhão</td><td>Instrumento para caracterização morfológica</td></tr><tr><td>bolacha de silício </td><td>Materiais Eletrônicos NOVA</td><td>HS39626</td><td></td></tr><tr><td>Adesivo de silicone</td><td>WPI</td><td>KWIK-SIL-S</td><td>Encapsulação</td></tr><tr><td>Borato de sódio</td><td>Sigma Aldrich</td><td>SX0355</td><td></td></tr><tr><td>Bolacha SOI</td><td>Ultrasil</td><td>3-10541</td><td>Tipo-Oriente:P/B(100) DT:7+/-1um DR:<. 005 ohmcm ht: 300 +/- 10um hr: 1-30 ohmcm caixa: 1um +/- 5% ud-13998 / uh-13962</td></tr><tr><td>SU-8 2002</td><td>Microquímicos</td><td>Série SU-8 2000</td><td></td></tr><tr><td>Desenvolvedor SU-8</td><td>Microquímicos</td><td>Série SU-8 2000</td><td></td></tr><tr><td>Adesivo de tecido úmido</td><td>3M</td><td>1469SB</td><td></td></tr><tr><td>Papel de filtro qualitativo Whatman, Grau 1</td><td>Sigma Aldrich</td><td>WHA1001150</td><td>Substrato para padronização de carbono</td></tr></tbody></table>

interfaces elétricas e optoeletrônicas bidirecionais em corações de ratos ex vivo saudáveis e isquêmicos

Bidirectional Electrical and Optoelectronic Interfaces in Healthy and Ischemic Ex Vivo Rat Hearts

Interfaces elétricas e optoeletrônicas bidirecionais em corações de ratos ex vivo saudáveis e isquêmicos

Electrophysiological studies are pivotal in exploring interactions between materials and cardiac biointerfaces. Recent advancements have introduced ...

bidirectional-electrical-optoelectronic-interfaces-healthy-ischemic

Research

JoVE Journal

Bioengineering

Bioengenharia

Este artigo descreve uma técnica de alta resolução temporal e espacial, visualmente, movimento de ação potencial imagem sobre a superfície de corações de ratos perfundidos Langendorff-utilizando um corante potenciométrica (di-8-ANEPPS).

Mapeamento óptica de corações perfundidos Langendorff-Rat

Este artigo descreve os procedimentos básicos para a realização de experimentos de mapeamento óptico no coração de coelho Langendorff-perfundidos usando o sistema de imagem panorâmica, ea modalidade de imagem dupla (tensão e cálcio).

Multiparamétrico Mapping Optical do Coração Coelho Langendorff-perfundidos

O objetivo deste estudo foi estabelecer um método de investigação da dinâmica cardíaca por meio de um modelo animal translacional. A abordagem experimental descrita incorpora optocardiografia de dupla emissão em conjunto com um estudo eletrofisiológico para avaliar a atividade elétrica em um modelo cardíaco suíno isolado e intacto.

Estudos de Optocardiografia e Eletrofisiologia de Ex Vivo Langendorff-perfundido Corações

Este protocolo descreve o procedimento de secção e cultivo de fatias cardíacas humanas para testes de drogas pré-clínicos e detalha o uso de mapeamento óptico para o registro de tensão transmembrana e sinais de cálcio intracelular simultaneamente a partir dessas fatias.

Avaliação de Eletrofisiologia Cardíaca Pré-Plínica por Mapeamento Óptico de Dupla Tensão e Cálcio de Fatias Cardíacas Organotípicas Humanas

Este artigo apresenta um método eficiente para realizar isquemia miocárdica e subsequente reperfusão crônica em ratos usando uma abordagem minimamente invasiva. Além disso, a função hemodinâmica ventricular esquerda dos ratos é avaliada por ecocardiografia e métodos cardíacos de trabalho isolados.

Método invasivo semi-mínimo para induzir infarto do miocárdio em ratos e a avaliação da função cardíaca por um sistema cardíaco de trabalho isolado

Este trabalho relata um método de controle do ritmo cardíaco de corações murinos intactos de camundongos transgênicos com canalrodopsina-2 (ChR2) utilizando fotoestimulação local com matriz micro-LED e mapeamento óptico simultâneo do potencial de membrana epicárdica.

Gerenciamento Avançado do Ritmo Cardíaco Aplicando Fotoestimulação Optogenética Multi-Site em Corações Murinos

Este protocolo introduz o mapeamento óptico dual-dye de corações de camundongos obtidos de animais selvagens e knock-in afetados por taquicardia ventricular polimórfica catecolaminérgica, incluindo medidas eletrofisiológicas de voltagem transmembrana e transientes intracelulares de Ca2+ com alta resolução temporal e espacial.

Mapeamento Óptico de Coração de Camundongos RyR2R2474S Knock-In de Taquicardia Ventricular Polimórfica Catecolaminérgica

Este protocolo ilustra um método para estimulação optogenética de neurônios cardíacos intrínsecos em corações de camundongos transgênicos. A abordagem descrita é usada para investigar a cinética da ativação súbita de neurônios cardíacos em corações perfundidos ex vivo e as interações entre a atividade colinérgica e catecolaminérgica.

Ativação optogenética de neurônios autônomos cardíacos intrínsecos em corações de camundongos perfundidos excisados

Um sistema de cultura de 3D para a hematopoiese é descrito usando sangue do cordão umbilical humano e células de medula óssea leucémicas. O método baseia-se na utilização de um poliuretano poroso sintético andaime revestido com proteínas da matriz extracelular. Este andaime é adaptável para acomodar uma grande variedade de células.

Ex vivo Mimetismo de normal e anormal Hematopoese Humanos

Teste de microtração ambientalmente controlado mecanicamente adaptativas nanocompósitos poliméricos para<em&gt; Ex vivo</em&gt; Caracterização

Explore interfaces ópticas e elétricas bidirecionais em corações de ratos ex vivo saudáveis e isquêmicos usando eletrodos de carbono nanoporo e membranas optoeletrônicas. Este método avança a pesquisa em bioeletrônica cardíaca.

Interfaces elétricas e optoeletrônicas bidirecionais em corações de ratos ex vivo saudáveis e isquêmicos

Explorar mais vídeos