Name: Terapia de Estimulação Magnética Transcraniana Personalizada Guiada por fMRI, Entregue Robóticamente para Depressão Resistente ao Tratamento (Vídeo) | JoVE Journal
Uploaded: 2026-04-10T12:43:00.000+00:00
Duration: 13 min 18 s
Description: Aprenda a implementar estimulação magnética transcraniana personalizada guiada por fMRI e entregue roboticamente para depressão resistente ao tratamento. Este protocolo demonstra como otimizar a precisão terapêutica através de conectividade funcional individualizada.

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<ol><li>O’reardon, J. P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Efficacy+and+safety+of+transcranial+magnetic+stimulation+in+the+acute+treatment+of+major+depression%3A+A+multisite+randomized+controlled+trial%5BTitle%5D)+AND+%22Biol+Psychiatry%22%5BJournal%5D)">Efficacy and safety of transcranial magnetic stimulation in the acute treatment of major depression: A multisite randomized controlled trial.</a> Biol Psychiatry. 62 (11), 1208-1216 (2007).</li>
<li>Luehr, J. G., Fritz, E., Turner, M., Schupp, C., Sackeim, H. A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Accelerated+transcranial+magnetic+stimulation%3A+A+pilot+study+of+safety+and+efficacy+using+a+pragmatic+protocol%5BTitle%5D)+AND+%22Brain+Stimulat+Basic+Translat+Clin+Res+Neuromodulat%22%5BJournal%5D)">Accelerated transcranial magnetic stimulation: A pilot study of safety and efficacy using a pragmatic protocol.</a> Brain Stimulat Basic Translat Clin Res Neuromodulat. 17 (4), 860-863 (2024).</li>
<li>Ramos, M. R. F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Accelerated+theta-burst+stimulation+for+treatment-resistant+depression%3A+A+randomized+clinical+trial%5BTitle%5D)+AND+%22JAMA+Psychiatry%22%5BJournal%5D)">Accelerated theta-burst stimulation for treatment-resistant depression: A randomized clinical trial.</a> JAMA Psychiatry. 82 (5), 442-450 (2025).</li>
<li>Blumberger, D. M., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effectiveness+of+theta+burst+versus+high-frequency+repetitive+transcranial+magnetic+stimulation+in+patients+with+depression+%28three-d%29%3A+A+randomised+non-inferiority+trial%5BTitle%5D)+AND+%22Lancet%22%5BJournal%5D)">Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (three-d): A randomised non-inferiority trial.</a> Lancet. 391 (10131), 1683-1692 (2018).</li>
<li>Cole, E. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Stanford+neuromodulation+therapy+%28snt%29%3A+A+double-blind+randomized+controlled+trial%5BTitle%5D)+AND+%22Am+J+Psychiatry%22%5BJournal%5D)">Stanford neuromodulation therapy (snt): A double-blind randomized controlled trial.</a> Am J Psychiatry. 179 (2), 132-141 (2022).</li>
<li>Fox, M. D., Halko, M. A., Eldaief, M. C., Pascual-Leone, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Measuring+and+manipulating+brain+connectivity+with+resting+state+functional+connectivity+magnetic+resonance+imaging+%28fcmri%29+and+transcranial+magnetic+stimulation+%28tms%29%5BTitle%5D)+AND+%22Neuroimage%22%5BJournal%5D)">Measuring and manipulating brain connectivity with resting state functional connectivity magnetic resonance imaging (fcmri) and transcranial magnetic stimulation (tms).</a> Neuroimage. 62 (4), 2232-2243 (2012).</li>
<li>Fox, M. D., Liu, H., Pascual-Leone, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Identification+of+reproducible+individualized+targets+for+treatment+of+depression+with+tms+based+on+intrinsic+connectivity%5BTitle%5D)+AND+%22Neuroimage%22%5BJournal%5D)">Identification of reproducible individualized targets for treatment of depression with tms based on intrinsic connectivity.</a> Neuroimage. 66, 151-160 (2013).</li>
<li>Cash, R. F., Cocchi, L., Lv, J., Fitzgerald, P. B., Zalesky, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Functional+magnetic+resonance+imaging%E2%80%93guided+personalization+of+transcranial+magnetic+stimulation+treatment+for+depression%5BTitle%5D)+AND+%22JAMA+Psychiatry%22%5BJournal%5D)">Functional magnetic resonance imaging–guided personalization of transcranial magnetic stimulation treatment for depression.</a> JAMA Psychiatry. 78 (3), 337-339 (2021).</li>
<li>Cash, R. F., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Personalized+connectivity-guided+dlpfc-tms+for+depression%3A+Advancing+computational+feasibility%2C+precision+and+reproducibility%5BTitle%5D)+AND+%22Human+Brain+Mapping%22%5BJournal%5D)">Personalized connectivity-guided dlpfc-tms for depression: Advancing computational feasibility, precision and reproducibility.</a> Human Brain Mapping. 42 (13), 4155-4172 (2021).</li>
<li>Siddiqi, S. H., Weigand, A., Pascual-Leone, A., Fox, M. D. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Identification+of+personalized+transcranial+magnetic+stimulation+targets+based+on+subgenual+cingulate+connectivity%3A+An+independent+replication%5BTitle%5D)+AND+%22Biol+Psychiatry%22%5BJournal%5D)">Identification of personalized transcranial magnetic stimulation targets based on subgenual cingulate connectivity: An independent replication.</a> Biol Psychiatry. 90 (10), e55-e56 (2021).</li>
<li>Hearne, L. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Clinical+and+neurophysiological+effects+of+robotically-delivered+fmri-guided+personalized+transcranial+magnetic+stimulation+therapy+for+depression%5BTitle%5D)+AND+%22Psychother+Psychosomat%22%5BJournal%5D)">Clinical and neurophysiological effects of robotically-delivered fmri-guided personalized transcranial magnetic stimulation therapy for depression.</a> Psychother Psychosomat. 94 (4), 225-331 (2025).</li>
<li>Cole, E. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Stanford+accelerated+intelligent+neuromodulation+therapy+for+treatment-resistant+depression%5BTitle%5D)+AND+%22Am+J+Psychiatry%22%5BJournal%5D)">Stanford accelerated intelligent neuromodulation therapy for treatment-resistant depression.</a> Am J Psychiatry. 177 (8), 716-726 (2020).</li>
<li>Koh, J. Z. J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Personalized+transcranial+magnetic+stimulation+treatment+for+depression%3A+An+open+label+pilot+trial%5BTitle%5D)+AND+%22Brain+Stimulat+Basic+Translat+Clin+Res+Neuromodulat%22%5BJournal%5D)">Personalized transcranial magnetic stimulation treatment for depression: An open label pilot trial.</a> Brain Stimulat Basic Translat Clin Res Neuromodulat. 18 (1), 480-481 (2025).</li>
<li>Montgomery, S. A., Åsberg, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+new+depression+scale+designed+to+be+sensitive+to+change%5BTitle%5D)+AND+%22Br+J+Psychiatry%22%5BJournal%5D)">A new depression scale designed to be sensitive to change.</a> Br J Psychiatry. 134 (4), 382-389 (1979).</li>
<li>Hamilton, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+assessment+of+anxiety+states+by+rating%5BTitle%5D)+AND+%22Br+J+Med+Psychol%22%5BJournal%5D)">The assessment of anxiety states by rating.</a> Br J Med Psychol. 32 (1), 50-55 (1959).</li>
<li>Zigmond, A. S., Snaith, R. P. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+hospital+anxiety+and+depression+scale%5BTitle%5D)+AND+%22Acta+Psychiatrica+Scandinavica%22%5BJournal%5D)">The hospital anxiety and depression scale.</a> Acta Psychiatrica Scandinavica. 67 (6), 361-370 (1983).</li>
<li>Sforzini, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+delphi-method-based+consensus+guideline+for+definition+of+treatment-resistant+depression+for+clinical+trials%5BTitle%5D)+AND+%22Mol+Psychiatry%22%5BJournal%5D)">A delphi-method-based consensus guideline for definition of treatment-resistant depression for clinical trials.</a> Mol Psychiatry. 27 (3), 1286-1299 (2022).</li>
<li>Li, X., Morgan, P. S., Ashburner, J., Smith, J., Rorden, C. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+first+step+for+neuroimaging+data+analysis%3A+Dicom+to+nifti+conversion%5BTitle%5D)+AND+%22J+Neurosci+Meth%22%5BJournal%5D)">The first step for neuroimaging data analysis: Dicom to nifti conversion.</a> J Neurosci Meth. 264, 47-56 (2016).</li>
<li>Esteban, O., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Fmriprep%3A+A+robust+preprocessing+pipeline+for+functional+mri%5BTitle%5D)+AND+%22Nat+Meth%22%5BJournal%5D)">Fmriprep: A robust preprocessing pipeline for functional mri.</a> Nat Meth. 16 (1), 111-116 (2019).</li>
<li>Van Essen, D. C., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+human+connectome+project%3A+A+data+acquisition+perspective%5BTitle%5D)+AND+%22Neuroimage%22%5BJournal%5D)">The human connectome project: A data acquisition perspective.</a> Neuroimage. 62 (4), 2222-2231 (2012).</li>
<li>Cocchi, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Effects+of+transcranial+magnetic+stimulation+of+the+rostromedial+prefrontal+cortex+in+obsessive%E2%80%93compulsive+disorder%3A+A+randomized+clinical+trial%5BTitle%5D)+AND+%22Na+Mental+Health%22%5BJournal%5D)">Effects of transcranial magnetic stimulation of the rostromedial prefrontal cortex in obsessive–compulsive disorder: A randomized clinical trial.</a> Na Mental Health. 1 (8), 555-563 (2023).</li>
<li>Cocchi, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Transcranial+magnetic+stimulation+in+obsessive-compulsive+disorder%3A+A+focus+on+network+mechanisms+and+state+dependence%5BTitle%5D)+AND+%22NeuroImage+Clin%22%5BJournal%5D)">Transcranial magnetic stimulation in obsessive-compulsive disorder: A focus on network mechanisms and state dependence.</a> NeuroImage Clin. 19, 661-674 (2018).</li>
<li>Bouaziz, N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Real+world+transcranial+magnetic+stimulation+for+major+depression%3A+A+multisite%2C+naturalistic%2C+retrospective+study%5BTitle%5D)+AND+%22J+Affective+Disord%22%5BJournal%5D)">Real world transcranial magnetic stimulation for major depression: A multisite, naturalistic, retrospective study.</a> J Affective Disord. 326, 26-35 (2023).</li>
<li>Cao, X., Deng, C., Su, X., Guo, Y. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Response+and+remission+rates+following+high-frequency+vs.+Low-frequency+repetitive+transcranial+magnetic+stimulation+%28rtms%29+over+right+dlpfc+for+treating+major+depressive+disorder+%28mdd%29%3A+A+meta-analysis+of+randomized%2C+double-blind+trials%5BTitle%5D)+AND+%22Front+Psychiatry%22%5BJournal%5D)">Response and remission rates following high-frequency vs. Low-frequency repetitive transcranial magnetic stimulation (rtms) over right dlpfc for treating major depressive disorder (mdd): A meta-analysis of randomized, double-blind trials.</a> Front Psychiatry. 9, 413(2018).</li>
<li>Risk, B. B., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Which+multiband+factor+should+you+choose+for+your+resting-state+fmri+study%5BTitle%5D)+AND+%22NeuroImage%22%5BJournal%5D)">Which multiband factor should you choose for your resting-state fmri study.</a> NeuroImage. 234, 117965(2021).</li>
<li>Kong, R., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Network-based+near-scalp+personalized+brain+stimulation+targets%5BTitle%5D)+AND+%22bioRxiv%22%5BJournal%5D)">Network-based near-scalp personalized brain stimulation targets.</a> bioRxiv. , (2025).</li>
<li>Bai, W., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Robot-assisted+transcranial+magnetic+stimulation+%28robo-tms%29%3A+A+review%5BTitle%5D)+AND+%22IEEE+Transact+Neural+Syst+Rehabilitat+Eng%22%5BJournal%5D)">Robot-assisted transcranial magnetic stimulation (robo-tms): A review.</a> IEEE Transact Neural Syst Rehabilitat Eng. 33, 2606-2621 (2025).</li>
<li>Yang, Z., Luo, N., Fan, L., Jiang, T. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Neuromodulation+robot+for+precision+tms%5BTitle%5D)+AND+%22Aperture+Neuro%22%5BJournal%5D)">Neuromodulation robot for precision tms.</a> Aperture Neuro. 5 (Suppl 1), (2025).</li>
<li>Faller, J., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Daily+prefrontal+closed-loop+repetitive+transcranial+magnetic+stimulation+%28rtms%29+produces+progressive+eeg+quasi-alpha+phase+entrainment+in+depressed+adults%5BTitle%5D)+AND+%22Brain+Stimulat%22%5BJournal%5D)">Daily prefrontal closed-loop repetitive transcranial magnetic stimulation (rtms) produces progressive eeg quasi-alpha phase entrainment in depressed adults.</a> Brain Stimulat. 15 (2), 458-471 (2022).</li>
<li>George, M. S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Eeg+synchronized+left+prefrontal+transcranial+magnetic+stimulation+%28tms%29+for+treatment+resistant+depression+is+feasible+and+produces+an+entrainment+dependent+clinical+response%3A+A+randomized+controlled+double+blind+clinical+trial%5BTitle%5D)+AND+%22Brain+Stimulat%22%5BJournal%5D)">Eeg synchronized left prefrontal transcranial magnetic stimulation (tms) for treatment resistant depression is feasible and produces an entrainment dependent clinical response: A randomized controlled double blind clinical trial.</a> Brain Stimulat. 16 (6), 1753-1763 (2023).</li>
<li>Pantazatos, S. P., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((The+timing+of+transcranial+magnetic+stimulation+relative+to+the+phase+of+prefrontal+alpha+EEG+modulates+downstream+target+engagement%5BTitle%5D)+AND+%22Brain+Stimulat%22%5BJournal%5D)">The timing of transcranial magnetic stimulation relative to the phase of prefrontal alpha EEG modulates downstream target engagement.</a> Brain Stimulat. 16 (3), 830-839 (2023).</li>
<li>Desouza, D. D., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Naturalistic+outcomes+with+fmri-guided+and+non-fmri-guided+accelerated+tms+for+depression%5BTitle%5D)+AND+%22medRxiv%22%5BJournal%5D)">Naturalistic outcomes with fmri-guided and non-fmri-guided accelerated tms for depression.</a> medRxiv. , (2025).</li>
<li>Cole, E., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((accelerated+intelligent+neuromodulation+therapy+for+treatment-resistant+depression+%28saint-trd%29%5BTitle%5D)+AND+%22Brain+Stimulat+Basic+Translat+Clin+Res+Neuromodulat%22%5BJournal%5D)">accelerated intelligent neuromodulation therapy for treatment-resistant depression (saint-trd).</a> Brain Stimulat Basic Translat Clin Res Neuromodulat. 12 (2), 402(2019).</li>
<li>Richter, L., Matthäus, L., Schlaefer, A., Schweikard, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Fast+robotic+compensation+of+spontaneous+head+motion+during+transcranial+magnetic+stimulation+%28tms%29%5BTitle%5D)+AND+%22UKACC+Int+Conf+CONTROL+2010%22%5BJournal%5D)">Fast robotic compensation of spontaneous head motion during transcranial magnetic stimulation (tms).</a> UKACC Int Conf CONTROL 2010. , (2010).</li>
<li>Cocchi, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Functional+alterations+of+large-scale+brain+networks+related+to+cognitive+control+in+obsessive-compulsive+disorder%5BTitle%5D)+AND+%22Human+Brain+Mapping%22%5BJournal%5D)">Functional alterations of large-scale brain networks related to cognitive control in obsessive-compulsive disorder.</a> Human Brain Mapping. 33 (5), 1089-1106 (2012).</li>
<li>Naze, S., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Mechanisms+and+interventions+promoting+healthy+frontostriatal+dynamics+in+obsessive-compulsive+disorder%5BTitle%5D)+AND+%22Nat+Comm%22%5BJournal%5D)">Mechanisms and interventions promoting healthy frontostriatal dynamics in obsessive-compulsive disorder.</a> Nat Comm. 16 (1), 7400(2025).</li>
<li>Webb, L., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Altered+striatal+functional+gradients+in+obsessive-compulsive+disorder%5BTitle%5D)+AND+%22Biol+Psychiatry+Cognitive+Neurosci+Neuroimag%22%5BJournal%5D)">Altered striatal functional gradients in obsessive-compulsive disorder.</a> Biol Psychiatry Cognitive Neurosci Neuroimag. 10 (11), 1134-1142 (2025).</li>
<li>Cocchi, L., Zalesky, A. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Personalized+transcranial+magnetic+stimulation+in+psychiatry%5BTitle%5D)+AND+%22Biol+Psychiatry+Cognitive+Neurosci+Neuroimag%22%5BJournal%5D)">Personalized transcranial magnetic stimulation in psychiatry.</a> Biol Psychiatry Cognitive Neurosci Neuroimag. 3 (9), 731-741 (2018).</li>
<li>De Souza, D. N., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Focused+ultrasound+as+an+emerging+therapy+for+neuropsychiatric+disease%3A+Historical+perspectives+and+a+review+of+current+clinical+data%5BTitle%5D)+AND+%22Psychiatry+Clin+Neurosci%22%5BJournal%5D)">Focused ultrasound as an emerging therapy for neuropsychiatric disease: Historical perspectives and a review of current clinical data.</a> Psychiatry Clin Neurosci. 79 (5), 215-228 (2025).</li>
<li>Riva-Posse, P., Figee, M. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((A+safe+step+in+the+right+direction%3A+Focused+ultrasound+in+obsessive-compulsive+disorder+and+depression%5BTitle%5D)+AND+%22Biol+Psychiatry%22%5BJournal%5D)">A safe step in the right direction: Focused ultrasound in obsessive-compulsive disorder and depression.</a> Biol Psychiatry. 97 (7), 664-665 (2025).</li>
<li>Gorgolewski, K., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Nipype%3A+A+flexible%2C+lightweight%2C+and+extensible+neuroimaging+data+processing+framework+in+Python%5BTitle%5D)+AND+%22Front+Neuroinfo%22%5BJournal%5D)">Nipype: A flexible, lightweight, and extensible neuroimaging data processing framework in Python.</a> Front Neuroinfo. 5, 13(2011).</li>
<li>Wang, H. T., et al. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Continuous+evaluation+of+denoising+strategies+in+resting-state+fmri+connectivity+using+fmriprep+and+nilearn%5BTitle%5D)+AND+%22PLoS+Computat+Biol%22%5BJournal%5D)">Continuous evaluation of denoising strategies in resting-state fmri connectivity using fmriprep and nilearn.</a> PLoS Computat Biol. 20 (3), e1011942(2024).</li>
<li>Avants, B. B., Tustison, N., Song, G. <a target="_blank" href="http://www.ncbi.nlm.nih.gov/pubmed?term=((Advanced+normalization+tools+%28ANTS%29%5BTitle%5D)+AND+%22Insight+J%22%5BJournal%5D)">Advanced normalization tools (ANTS).</a> Insight J. 2 (365), 1-35 (2009).</li>
</ol>

<table><tbody><tr><td>Bobina de cabeça e braço de 64 canais</td><td>Siemens</td><td>10606850</td><td></td></tr><tr><td>Serviço de computação em nuvem</td><td>Amazon</td><td>https://aws.amazon.com/?refid=536ef9fe-bc1d-4318-ae84-3df0523ed98a</td><td></td></tr><tr><td>Cobot</td><td>Axilum</td><td>https://www.axilumrobotics.com/en/</td><td>Este cobot possui integração específica de software e hardware com o sistema de neuronavegação e a bobina.</td></tr><tr><td>DCM2NIIX</td><td>Laboratório Rordern</td><td>https://www.nitrc.org/plugins/mwiki/index.php/dcm2nii:MainPage; https://github.com/rordenlab/dcm2niix</td><td>Veja https://www.nitrc.org/plugins/mwiki/index.php/dcm2nii:MainPage; https://github.com/rordenlab/dcm2niix para o manual de operações. &nbsp;</td></tr><tr><td>fMRIPrep</td><td>NiPreps</td><td>https://fmriprep.org/en/stable/api.html</td><td>Ferramenta de software de código aberto para pré-processamento de fMRI, veja https://fmriprep.org/en/stable/ para o manual de operações.</td></tr><tr><td>Máquina de ressonância magnética</td><td>Siemens</td><td>166026</td><td>3 Tesla de intensidade.</td></tr><tr><td>MRICron</td><td>NITRC</td><td>https://www.nitrc.org/projects/mricron</td><td>Ferramenta de software de código aberto para visualização de imagens de ressonância magnética, veja https://www.nitrc.org/projects/mricron para o manual de operações.</td></tr><tr><td>Câmera de neuronavegação</td><td>Northern Digital Inc.</td><td>P7-11191</td><td>Esta câmera de neuronavegação, e outras na linha do mesmo fabricante&nbsp; são compatíveis com o TMS Navigator</td></tr><tr><td>Bobina TMS</td><td>MagVenture</td><td>9016 E0151</td><td>Essa bobina foi projetada para integrar hardware ao braço robótico Cobot e vem com seu próprio sistema de refrigeração.&nbsp;</td></tr><tr><td>Sistema de neuronavegação TMS</td><td>Localização</td><td>10225</td><td>Esse sistema de neuronavegação possui funções de software integradas específicas com o cobot e o estimulador TMS.</td></tr><tr><td>Estimulador TMS</td><td>MagVenture A/S</td><td>&nbsp; 9016E0721</td><td>Este sistema de estimulação TMS foi projetado para integrar-se à bobina e ao sistema de neuronavegação para feedback de estimulação (por exemplo, número de pulsos, registro de potencial evocado motor). &nbsp;</td></tr></tbody></table>

terapia de estimulação magnética transcraniana personalizada guiada por fmri, entregue robóticamente para depressão resistente ao tratamento

Robotically Delivered fMRI-Guided Personalized Transcranial Magnetic Stimulation Therapy for Treatment-Resistant Depression

Terapia de Estimulação Magnética Transcraniana Personalizada Guiada por fMRI, Entregue Robóticamente para Depressão Resistente ao Tratamento

Improving the outcomes of transcranial magnetic stimulation (TMS) therapy for treatment-resistant depression may be achieved by personalizing the ...

robotically-delivered-fmri-guided-personalized-transcranial-magnetic

Research

JoVE Journal

Neuroscience

Neurociência

Fonte: Dunlop, K., et al. dmPFC-rTMS guiado por ressonância magnética como tratamento para transtorno depressivo maior resistente ao tratamento. J. Vis. Exp. (2015)Este vídeo demonstra o procedimento de estimulação magnética transcraniana repetitiva (rTMS) guiada por ressonância magnética direcionada ao córtex pré-frontal dorsomedial (dmPFC) para tratar a depressão.

Estimulação magnética transcraniana repetitiva guiada por ressonância magnética para o córtex pré-frontal dorsomedial

Aqui descrevemos o procedimento para estimulação magnética transcraniana repetitiva guiada por ressonância magnética para o córtex pré-frontal dorsomedial como um tratamento experimental para transtorno depressivo maior.

Guiada por MRI dmPFC-EMTr como um tratamento para o Transtorno Depressivo Maior resistente ao tratamento

Aqui apresentamos um protocolo que define a metodologia para tratamento de Transtorno Depressivo Maior usando o sistema profundo Estimulação Magnética Transcraniana (DTMs).

Tratar depressão clínica com Estimulação Magnética Transcraniana repetitiva profundo Usando o H1-coil Brainsway

O presente protocolo descreve a aplicação da estimulação magnética transcraniana repetitiva (rTMS), onde uma subregião do córtex pré-frontal dorsolateral (DLPFC) com a anticorrelação funcional mais forte com o córtex cingulado anterior subgenual (sgACC) foi localizada como alvo de estimulação sob a assistência de um sistema de neuronavigição baseado em FMRI.

Tratamento individualizado de rTMS para depressão usando um método de segmentação baseado em fMRI

Um novo protocolo para estimulação magnética transcraniana personalizada em combinação com mapeamento de eletroencefalografia (TMS-EEG) de redes corticais, informado por múltiplas modalidades de dados de ressonância magnética (MRI).

TMS-EEG guiado por neuroimagem para mapeamento de rede cortical em tempo real

Este protocolo apresenta um guia para a aplicação precisa e centrada no paciente da estimulação magnética transcraniana repetitiva para depressão maior resistente ao tratamento. São fornecidos detalhes sobre procedimentos para localização precisa da bobina, dosagem ajustável de estímulos, medidas rigorosas de segurança e estratégias que maximizam conforto, reprodutibilidade e eficácia clínica a longo prazo em sessões agudas e de manutenção.

Estimulação Magnética Transcraniana Repetitiva Convencional para Depressão: Um Protocolo Passo a Passo

Fosfenos são percepts transitória de luz que pode ser induzida pela aplicação de Estimulação Magnética Transcraniana (TMS) para regiões sensíveis do córtex visual. Demonstramos um protocolo padrão para determinar o valor limite fosfeno e introduzir um novo método para quantificar e analisar fosfenos percebido.

Uma nova abordagem para a Documentação fosfenos induzidos por estimulação magnética transcraniana

Neste artigo, vamos examinar a metodologia e considerações relevantes para a combinação de TMS e fMRI para examinar os efeitos de estimulação cerebral na rede padrão.

Combinando Estimulação Magnética Transcraniana e fMRI para o Exame da rede de modo padrão

Neste artigo, vamos examinar os efeitos da dependência do Estado visualmente relevantes sobre TMS induzida apresentações phosphenic motivo.

Estado de dependência-Efeitos sobre a TMS: Um olhar sobre Comportamento fosfeno Motive

Neste artigo, vamos examinar a metodologia e considerações relevantes para o protocolo de tratamento aprovado pela FDA depressão usando o dispositivo Neuronetics NeuroStar TMS.

O dispositivo NeuroStar TMS: Conduzindo a FDA Aprovado protocolo para o tratamento da depressão

Aprenda a implementar estimulação magnética transcraniana personalizada guiada por fMRI e entregue roboticamente para depressão resistente ao tratamento. Este protocolo demonstra como otimizar a precisão terapêutica através de conectividade funcional individualizada.

Terapia de Estimulação Magnética Transcraniana Personalizada Guiada por fMRI, Entregue Robóticamente para Depressão Resistente ao Tratamento (Vídeo) | JoVE Journal

Terapia de Estimulação Magnética Transcraniana Personalizada Guiada por fMRI, Entregue Robóticamente para Depressão Resistente ao Tratamento

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