Биопечать гидрогелевых срезов опухоли в качестве 3D-модели мантийноклеточной лимфомы

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12 сентября 2025 г.

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Julia Thiel¹ , Jan A. Schlegel¹ , Sam Steinfeldt¹ , Kathrin Baader Böpple¹ , Chen Xing¹^,² , Annette M. Staiger¹^,³ , Heike Horn¹^,³ , Kathrin S. Kurz³ , German Ott³ , Walter E. Aulitzky⁴ , Matthias Schwab¹^,⁵^,⁶^,⁷^,⁸ , Thomas E. Mürdter¹ , Meng Dong¹

¹Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tuebingen, ²Department of Physiology and Pharmacology, Karolinska Institute, ³Department of Clinical Pathology, Robert Bosch Hospital, ⁴Robert Bosch Hospital, ⁵Departments of Clinical Pharmacology, Pharmacy and Biochemistry, University of Tuebingen, ⁶iFIT Cluster of Excellence (EXC 2180), Image-guided and Functionally Instructed Tumor Therapies, University of Tuebingen, ⁷German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Partner Site Tuebingen, ⁸National Center for Tumor Diseases (NCT), NCT South-West, a partnership between DKFZ, University Hospital Tuebingen, University of Tuebingen, Tuebingen, Bosch Health Campus, Stuttgart, Robert Bosch Hospital, Stuttgart, University Hospital Ulm, and Ulm University

Этот протокол содержит подробное описание генерации, культивирования и анализа мантийноклеточной лимфомы в гидрогелевых срезах опухоли, напечатанных на 3D-принтере.

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