go to jove.com

HIGH SCHOOL

Biology

Concept Videos

Biology

This is a free preview. For full access

Metabolism

Phosphorylation and Protein Control

Description

Phosphorylation helps control how proteins work in cells. It is the addition or removal of phosphate groups, and it is the most common chemical change that regulates cellular processes. These changes can alter a protein’s structure, activity, stability, location inside the cell, and interactions with other proteins.

Transcript

Phosphorylation, the addition of a phosphate group, is an important chemical modification that helps cells to regulate protein function.

During phosphorylation, protein kinases transfer the terminal phosphate group of ATP to specific amino acid side chains of a target protein.

As a result, the target protein may change conformation...

Tags

Protein PhosphorylationProtein KinasesProtein PhosphatasesAmino Acid PhosphorylationATP HydrolysisDephosphorylationProtein Function RegulationTau ProteinAlzheimer s DiseaseCellular Signaling

More videos by Standards