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Chemistry

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Analytical Chemistry

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Advanced Nuclear Magnetic Resonance Spectroscopy

Reading Proton Coupling with COSY Maps

Description

COSY is a 2-dimensional NMR method that shows which protons are coupled to each other. It is used to spot geminal and vicinal coupling in a sample. This makes it helpful for reading proton relationships in complex spectra.

The ethyl acetate example shows how COSY is built from the 1D proton NMR s...

Transcript

Homonuclear correlation spectroscopy or COSY is a 2D NMR technique that identifies coupled protons.

Consider the COSY spectrum of ethyl acetate. The corresponding 1D proton NMR spectrum is plotted along the horizontal and vertical axes.

The three spots on the diagonal correspond to the three peaks in the 1D spectrum, making COSY sp...

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