Gene Regulation by Co-activators and Co-repressors

Co-activators and co-repressors help control gene expression. They do not usually bind DNA themselves. Instead, they work with transcription factors to change how strongly a gene is turned on or off.

Co-activators support transcription. They help transcription factors and RNA polymerase work toge...

Transcription is regulated by activators and repressors, proteins that bind to DNA. In eukaryotes, these regulatory proteins often need additional proteins, called co-regulators, to function properly.

These co-regulators bind to activator or repressor complexes; however, they do not recognize cis-regulatory sequences, as they can...