Sister Chromatid Attachment in Mitosis

Sister chromatid attachment in mitosis helps align duplicated chromosomes before they separate. Sister chromatids are the matching copies made after DNA replication. They stay connected until the cell is ready to divide.

The attachment step is closely tied to the metaphase plate, the middle of th...

During mitosis, following the assembly of a bipolar microtubule array, the kinetochore microtubules attach to the sister-chromatids.

Microtubules attach to each chromatid via the kinetochore located at the centromere. Multiple microtubules from the same spindle pole can bind to a single kinetochore to form the kinetochore fiber.

Th...