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Chemistry

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Analytical Chemistry

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Mass Spectrometry Fragmentation Methods

How MALDI Turns Samples Into Ions

Description

Matrix-assisted laser desorption ionization (MALDI) is a mass spectrometry technique that turns biomolecules into ions for analysis. It is used to identify and characterize proteins, peptides, nucleic acids, and carbohydrates. Because of this, it is common in biological and medical research, as well as pharmacology and bioch...

Transcript

Matrix-assisted laser desorption ionization, or MALDI, is an ionization technique employed to acquire accurate molecular mass data for polar biopolymers with molecular masses ranging from a few to a hundred thousand Daltons.

The sample preparation process involves mixing an analyte solution with a matrix material, such as 2,5-dihydroxybenz...

Tags

MALDI Mass SpectrometryProton Transfer IonizationTime of Flight Mass AnalyzerBiomolecule IdentificationProtein Peptide AnalysisNucleic Acid CharacterizationCarbohydrate DetectionAnalyte Matrix Mixture