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Microbiology

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Bacterial Diseases

Tetanus Toxin and Muscle Spasms

Description

Tetanus is a life-threatening neurological disorder that causes persistent muscle contractions and spastic paralysis. It is caused by Clostridium tetani, a motile, Gram-positive, rod-shaped, obligate anaerobe. The bacteria form terminal endospores, which give them a distinctive lollipop or tennis-racket appearance.

Transcript

Tetanus is a severe neuromuscular disorder characterized by sustained muscle spasms caused by the bacterium Clostridium tetani.

It is caused when Clostridium tetani spores enter the host through wounds and germinate under anaerobic conditions in damaged or necrotic tissue.

The germinated vegetative cells remain localize...

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