Building Carbon-Carbon Bonds with Grignard Reagents

Grignard reagents are useful organometallic compounds for building carbon-carbon bonds. This experiment shows how to make a Grignard reagent from magnesium and an alkyl halide. It then uses that reagent in a reaction with a carbonyl compound.

A nucleophilic attack on the carbonyl is carried out t...

The Grignard reaction is a useful tool for the formation of carbon-carbon bonds in organic synthesis.

This reaction was discovered more than a century ago by a French Chemist named Victor Grignard for which he was rewarded a Nobel Prize in 1912.

The Grignard reaction consists of two steps. The first step is reacting an organohalide w...