The authors have nothing to disclose.

predicting the effectiveness of population replacement strategy using mathematical modeling

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy.  Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies.  The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy. Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies. The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy.  ...

You can't do Experiments on the ecological scale because that isn't an experiment. It's the actual release. What if something goes wrong?Remember these mosquitoes transmit a number of very serious diseases. What if they become super bugs and they start transmitting even more effectively? Maybe they'll start transmitting other diseases that they had not been able to transmit in the past.We really have to formulate our policies based on computer models, just like having computer models for all contingencies in landing someone on the moon. So too, we have to have simulations of all contingencies for what happens after we release gene ape modified mosquitoes. My name's Charles Taylor.I'm a the univers of California Los Angeles in the Department of Ecology and Evolutionary Biology with my students and postdocs. I've been working on mathematical aspects of the attempt to use genetically modified mosquitoes to control malaria. We've taken several different approaches to doing this for different parts of the the problem.And today I'll show you a little bit of our work that we've done the last few years and I'll introduce you to one of my students, John Marshall. The modeling we've been doi

predicting-effectiveness-population-replacement-strategy-using

Research

JoVE Journal

Biology

University of California, Los Angeles.  Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy. Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies. The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

Summary

Charles Taylor and John Marshall explain the utility of mathematical modeling for evaluating the effectiveness of population replacement strategy. Insight is given into how computational models can provide information on the population dynamics of mosquitoes and the spread of transposable elements through A. gambiae subspecies. The ethical considerations of releasing genetically modified mosquitoes into the wild are discussed.

Predicting the Effectiveness of Population Replacement Strategy Using Mathematical Modeling

In This Article

Summary

Abstract

Disclosures

Reprints and Permissions

Explore More Articles