In Vivo MRI Analysis of Cranial Nerve Morphology in a Patient with Inner Ear Disorder

Abstract

Source: Flatz, W. H. et al. In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears. J. Vis. Exp. (2018).

This video demonstrates the use of MRI to analyze cranial nerve morphology in the ears of patients suffering from a chronic inner ear disorder. It outlines the steps for performing a high magnetic field MRI scan on the patient, reconstructing the high-resolution 3D cross-sectional images of the cranial nerves, and measuring nerve dimensions to evaluate the abnormalities.

Protocol

All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human welfare and have been reviewed by the local institutional review board.

Results

Materials

List of materials used in this article

Name	Company	Catalog Number	Comments
MR-scanner, e.g. Siemens Magnetom Verio, or appropriate MR-scans in DICOM format, e.g. 3D-CISS	Siemens Healthcare GmbH, Erlangen, Germany, or MR scans by any other vendor	1	Instead of the MR scanner, appropriately acquired MR-scans can be used for morphometric analysis
Osirix or any other DICOM-Viewer with appropriate evaluation tools	Pixmeo SARL, Geneva, Switzerland	2	Software for viewing and evaluating DICOM images
MedCalc or any other statistical analysis software, e.g. SPSS	MedCalc Software bvba, Ostend, Belgium	3	Software for statistical analysis
Computer running Windows or MacOSX/macOS	e.g. Lenovo, Apple or anything selfmade	4	Hardware on which the above software can be employed