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Method Article

Functional Imaging of Cerebral Blood Flow Using Transcranial Doppler Ultrasound

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May 29th, 2025

In This Article

Abstract

Source: Hage, B. D. et. al., Functional Transcranial Doppler Ultrasound for Monitoring Cerebral Blood Flow. J. Vis. Exp. (2021)

This video demonstrates the use of Doppler ultrasound as a functional imaging tool to measure cerebral blood flow velocity, or CBFV in real time. It highlights how frequency shifts in the middle cerebral artery during tasks like breath-holding reveal changes in CBFV, offering insights into brain activity and vascular dynamics.

Protocol

All procedures involving human participants have been performed in compliance with the institutional, national, and international guidelines for human welfare and have been reviewed by the local institutional review board.

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Results

Cerebral artery anatomy diagram; internal carotid artery (ICA), anterior (ACA), middle cerebral artery (MCA).

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Materials

List of materials used in this article
NameCompanyCatalog NumberComments
AquasonicParker Laboratories, Inc., Fairfield, NJ, USA01-50Ultrasound Gel
Doppler Box XDWL Compumedics Gmbh, Singen, GermanyModel "BoxX"Transcranial Doppler with 2-MHz monitoring probes
KimwipesKimberly-Clark Professional34256Delicate Task Wipers
TransepticParker Laboratories, Inc., Fairfield, NJ, USA09-25Cleaning Spray

Tags

Middle Cerebral ArteryDoppler ShiftBreath HoldingUltrasound GelFixation DeviceTCD SoftwareBlood Velocity