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Method Article

MixKNet: A Modified U-shaped Network with Hybrid Channel Convolution for Medical Image Segmentation

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DOI:

10.3791/68450

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July 15th, 2025

In This Article

Summary

This study presents a lightweight U-Net variant with improved segmentation accuracy using hybrid convolution and channel attention, achieving state-of-the-art results on MoNuseg and GlaS with fewer parameters.

Abstract

Artificial neural network-based computer image processing technology has rapidly developed in recent years and found widespread applications across multiple fields. In medical image processing, UNet and its variants have shown great success in lesion detection, cell segmentation, and polyp segmentation tasks. This research presents a modified U-shaped network with reduced network parameters achieved by decreasing the network depth and increasing the network channels to enhance the model's learning ability. To counteract the reduction in learning capacity caused by depth compression, a hybrid-channel convolutional module is introduced to replace the original network's convolutional module. The model introduces a channel attention mechanism between the layer and the point convolution layer to improve the practical channel feature extraction ability. The article also concludes that using mixed-depth convolution can effectively solve the size span of the segmentation target, making it difficult for one model to be fit for multiple data sets. The proposed model achieves state-of-the-art results on two popular public datasets, MoNuseg and GlaS, with a mean dice increase of 1.0% and 1.37%, respectively. The total parameters of the modified model are reduced to 1.71M, representing a 38.6x reduction compared to UCtransNet, with 65.6M parameters.

Introduction

Medical image segmentation is critical in various clinical applications, including diagnosis, treatment planning, and disease monitoring. Traditional image processing methods based on feature engineering algorithms are no longer suitable for handling the large volumes of data generated in modern healthcare environments. Fortunately, the advancement of artificial neural network technology and improvements in computer hardware capabilities have made it possible to train and deploy large-scale neural network models. As a result, computer vision processing algorithms based on machine learning models are continuously being developed and applied in various fields.

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Protocol

This section describes the proposed MixKNet architecture for medical image segmentation. The MixKNet model extends the UNet architecture, incorporating attention mechanisms and mixed depthwise convolution layers. The software used in this study is listed in the Table of Materials.

1. Overall architecture

  1. The MixKNet architecture, shown in Figure 2, follows the standard UNet structure, consisting of an encoder and a decoder. Set the input shape to 224 × 224 × 3. In the encoder, use two DownBlock modules-each includes a 1×1 depth-wise convolution, a 2&#....

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Results

Comparison with state-of-the-art methods
The MixKNet architecture has been evaluated on two medical image segmentation datasets, GlaS and MoNuSeg, and compared with state-of-the-art methods in the field. The evaluation has been conducted by reporting the dice and IoU scores of the proposed method and several comparable models, as shown in Table 3. The results indicate that the MixKNet architecture outperforms the other models, achieving the highest me.......

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Discussion

This study presents MixKNet, a novel modification of the UNet1 architecture for medical image segmentation, integrating mixed-depth convolution and a channel attention mechanism to enhance segmentation performance while significantly reducing computational complexity. The hybrid channel convolution combines multiple convolutional kernels operating on separate channel groups. This design allows the network to capture diverse spatial and contextual features at different receptive field scales within.......

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Disclosures

The authors declare no competing financial interests or other conflicts of interest.

Acknowledgements

The second batch of Ningbo City's 2023 Social Welfare Research Projects: Research and Application of Key Technologies for Telecom Network Fraud Identification Based on Ontology and NLP (2023S169).

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Materials

List of materials used in this article
NameCompanyCatalog NumberComments
Linux OS (Ubuntu 22.04) Various (Open Source Community)N/A(Version 22.04 LTS)Open-source operating system for development
https://releases.ubuntu.com/22.04/
NVIDIA RTX 3090 GPUNVIDIA3090High-performance GPU for deep learning
https://www.nvidia.com/en-us/geforce/graphics-cards/30-series/rtx-3090/
PythonPython Software FoundationN/A (Version ≥ 3.8)Programming language for AI/ML development
https://www.python.org/
PyTorchMeta AIN/A (Version 1.13)Open-source machine learning framework
https://pytorch.org/
Visual Studio Code (VS Code)MicrosoftN/ALightweight and powerful code editor
https://code.visualstudio.com/

References

  1. Ronneberger, O., Fischer, P., Brox, T. U-Net: Convolutional networks for biomedical image segmentation. Med Image Comput Comput Assist Interv. 9351, 234-241 (2015).
  2. Oktay, O., et al. Attention U-Net: Learning where to look for the pancreas. arXiv. , (2018).
  3. Alom, M. Z., Yakopcic, C., Hasan, M., Taha, T. ....

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Reprints and Permissions

Tags

U-Net VariantsChannel AttentionMixed-Depth ConvolutionLesion DetectionCell SegmentationPolyp SegmentationModel Parameter ReductionFeature Extraction

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