| Automatic Biochemical Analyzer | Roche Diagnostics (Shanghai) Co., Ltd. | cobas c 702 | Used for batch detection of core biochemical indicators in the study, including Fasting Plasma Glucose (FPG), 2-hour Postprandial Plasma Glucose (2hPG), Total Cholesterol (TC), Triglyceride (TG), Low-Density Lipoprotein Cholesterol (LDL-C), and High-Density Lipoprotein Cholesterol (HDL-C). Its detection accuracy meets the clinical laboratory standardization requirements, and provides core detection data for the study outcome indicators. |
|---|
| Blood Glucose (Glucose) Detection Reagent | Roche Diagnostics (Shanghai) Co., Ltd. | Matching Biochemical Reagent for cobas c 702 | Used in conjunction with the automatic biochemical analyzer for the accurate quantitative detection of glucose concentration in serum/plasma. It provides detection data for the core blood glucose indicators of FPG and 2hPG, and the inter-batch difference meets the clinical laboratory quality control standards. |
|---|
| Bluetooth Glucometer | Roche Diagnostics (Shanghai) Co., Ltd. | Accu-Chek Guide | Core home testing device for the study intervention, used for the detection of patients' fasting and 2-hour postprandial blood glucose. It supports automatic Bluetooth data synchronization to the study-specific WeChat Mini Program, can identify abnormal blood glucose values (>13.9 mmol/L or <3.9 mmol/L) and trigger alerts, and provides standardized data support for home-based dynamic blood glucose monitoring in elderly patients with diabetes. |
|---|
| Disposable EDTA-K2 Anticoagulant Blood Collection Tube | Becton, Dickinson and Company (BD), BD Medical Devices (Shanghai) Co., Ltd. | 2mL Anticoagulant Type | Used for collecting patients' whole blood samples. The EDTA-K2 anticoagulant can stabilize blood cell morphology, is compatible with the detection of Glycated Hemoglobin (HbA1c), and complies with the clinical blood sample collection specifications. |
|---|
| Disposable Intravenous Blood Collection Needle | Becton, Dickinson and Company (BD), BD Medical Devices (Shanghai) Co., Ltd. | 21G | Used in conjunction with vacuum blood collection tubes for the collection of patients' venous blood samples. It has a sterile disposable design, the specification is suitable for adult intravenous blood collection procedures, which reduces the risk of sample hemolysis and ensures the accuracy of test results. |
|---|
| Disposable Vacuum Coagulation-Promoting Blood Collection Tube | Becton, Dickinson and Company (BD), BD Medical Devices (Shanghai) Co., Ltd. | 3mL Conventional Coagulation-Promoting Type | Used for collecting patients' venous blood samples. The coagulant can accelerate blood coagulation, and the separated serum is compatible with the detection of biochemical indicators such as blood glucose and blood lipids. The disposable sterile design ensures the safety and standardization of sample collection. |
|---|
| Electronic Hand Dynamometer | Guangdong Xiangshan Weighing Apparatus Group Co., Ltd. | EH101 | Used for the accurate measurement of grip strength indicators in the Fried frailty phenotype assessment. It can quantitatively record the maximum hand grip strength, and judge the decline of muscle strength stratified by gender and BMI, fully complying with the standardized operation requirements for frailty assessment in this study. |
|---|
| Glycated Hemoglobin (HbA1c) Detection Reagent | Bio-Rad Laboratories, Inc. (USA) | Matching Reagent for Variant II Turbo | Used in conjunction with the glycated hemoglobin analyzer to detect HbA1c in whole blood samples by HPLC. It is used to evaluate the long-term blood glucose control level of patients, and is a special detection reagent for the core blood glucose outcome indicators of this study. |
|---|
| Handheld Laser Rangefinder | Deli Group Co., Ltd. | DL4168 | Used to accurately calibrate the standard distance of the 4-meter walking test, eliminate manual measurement errors, and ensure the consistency and accuracy of walking speed measurement in the Fried frailty phenotype assessment. |
|---|
| High-Density Lipoprotein Cholesterol (HDL-C) Detection Reagent | Roche Diagnostics (Shanghai) Co., Ltd. | Matching Biochemical Reagent for cobas c 702 | Used in conjunction with the automatic biochemical analyzer for the quantitative detection of HDL-C concentration in serum, to assist in the assessment of patients' lipid protective factors and cardiovascular disease risk. |
|---|
| High-Precision Electronic Stopwatch | Shenzhen Tianfu Electronics Co., Ltd. | PC894 | Used for timing measurement of 4-meter walking speed in the Fried frailty phenotype assessment, with a timing accuracy of 0.01 seconds. It provides accurate timing data for the judgment of frailty indicators related to slowed walking speed. |
|---|
| Hospital Information System (HIS) | Winning Health Technology Group Co., Ltd. | Winning HIS V5.0 | The core data source for patients' baseline data, clinical test results, and diagnosis and treatment records in this study. It can completely trace the full-cycle diagnosis and treatment information of patients, and ensure the authenticity, integrity and traceability of the study data. |
|---|
| HPLC Glycated Hemoglobin Analyzer | Bio-Rad Laboratories, Inc. (USA) | Variant II Turbo | Adopts High Performance Liquid Chromatography (HPLC) to detect Glycated Hemoglobin A1c (HbA1c). It is the gold standard equipment for evaluating the average blood glucose control level of diabetic patients in the past 2-3 months, and provides standardized and traceable test results for the blood glucose control outcomes of this study. |
|---|
| Low-Density Lipoprotein Cholesterol (LDL-C) Detection Reagent | Roche Diagnostics (Shanghai) Co., Ltd. | Matching Biochemical Reagent for cobas c 702 | Used in conjunction with the automatic biochemical analyzer for the quantitative detection of LDL-C concentration in serum. It is the core lipid indicator detection reagent for the risk assessment of cardiovascular complications in this study. |
|---|
| Medical Electronic Body Weight Scale | Huawei Device Co., Ltd. | AH100 | Used to accurately measure patients' body weight and calculate Body Mass Index (BMI). It is the core detection tool for the unintentional weight loss indicator in the Fried frailty phenotype, and also provides basic data for patients' body weight management and personalized dietary intervention. |
|---|
| Medical Low-Speed Centrifuge | Hunan Xiangyi Laboratory Instrument Development Co., Ltd. | TDZ5-WS | Used for the pretreatment of venous blood samples. It separates serum/plasma through standardized centrifugation to provide qualified samples for subsequent biochemical indicator testing such as blood glucose and blood lipids, and is compatible with the routine centrifugation parameter requirements for clinical laboratory testing. |
|---|
| SPSS Statistical Analysis Software | IBM Corporation (USA) | SPSS 26.0 | Used for the statistical analysis of the full set of clinical data in this study. It can perform a variety of statistical methods including normality test, independent samples t-test, paired t-test, chi-square test, Mann-Whitney U test, and repeated measures analysis of variance, with P<0.05 set as the threshold for statistical significance. |
|---|
| Total Cholesterol (TC) Detection Reagent | Roche Diagnostics (Shanghai) Co., Ltd. | Matching Biochemical Reagent for cobas c 702 | Used in conjunction with the automatic biochemical analyzer for the quantitative detection of total cholesterol concentration in serum, and provides core data for the assessment of patients' lipid metabolism status. |
|---|
| Triglyceride (TG) Detection Reagent | Roche Diagnostics (Shanghai) Co., Ltd. | Matching Biochemical Reagent for cobas c 702 | Used in conjunction with the automatic biochemical analyzer for the quantitative detection of triglyceride concentration in serum, to assist in the assessment of patients' abnormal lipid metabolism and cardiovascular disease risk. |
|---|
| Upper Arm Bluetooth Electronic Sphygmomanometer | Omron Healthcare (China) Co., Ltd. | HEM-7136T | Used in conjunction with the blood glucose monitoring module for automated home blood pressure testing of patients. It supports Bluetooth data synchronization to the multimedia management platform, and assists in the continuous monitoring and comprehensive management of patients' cardiovascular risk factors. |
|---|
| WeChat Mini Program for Home-Based Diabetes Management | Independently Developed by the Information Technology Department of the Study Hospital | https://weixin.ngarihealth.com/weixin/wx/mp/wx87e933682e320dea/index.html?pageModule=secHomepage | The core carrier of the intervention measures in this study, which includes six core modules: data monitoring, medication management, complication self-assessment, health knowledge push, expert live Q&A, and emergency contact. It realizes the full-process closed-loop management of home-based care for elderly diabetic patients, and supports automatic synchronization of blood glucose and blood pressure data as well as real-time alerts for abnormal values. |
|---|