Method Article

One-lung Ventilation in Pediatric Patients: Lung Isolation Techniques and Clinical Management

DOI:

10.3791/71007

May 5th, 2026

In This Article

Summary

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This review evaluates pediatric lung isolation techniques, emphasizing age-specific strategies: double-lumen tubes for children >8 years, intraluminal blockers for ages 2–8 years (ETT ID ≥4.5 mm), and extraluminal blockers or mainstem intubation for infants <2 years. It highlights how 3D printing and protective ventilation optimize safety.

Abstract

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Implementing one-lung ventilation (OLV) in pediatric patients presents unique clinical challenges due to age-dependent physiological and anatomical constraints. As minimally invasive thoracic surgery expands in pediatrics, the demand for precise lung isolation has increased. This narrative review evaluates current techniques—single-lumen tubes (SLT), double-lumen tubes (DLT), and bronchial blockers (BB)—with a focus on their safety profiles and clinical indications. Findings indicate that DLTs remain the benchmark for older children but are anatomically prohibitive for those under 8–10 years or shorter than 130 cm. BBs are the primary alternative for children aged 2–8 years (ETT ID ≥4.5 mm), although traditional devices such as the Arndt-Fogarty blockers have design limitations. For infants under 2 years, the primary strategies remain SLT mainstem intubation or extraluminal blocker placement, both of which carry a risk of right upper lobe (RUL) obstruction. Emerging innovations, particularly 3D-printed anatomically customized blockers, are highlighted as potential solutions to resolve device “fit” challenges in infants. Perioperative management remains non-standardized; however, evidence-based recommendations emphasize lung-protective ventilation to reduce pulmonary complications. Hypoxemia occurs in approximately 26% of pediatric OLV cases and requires a prioritized management framework that includes fiberoptic verification, secretion clearance, and optimized PEEP/CPAP application. By synthesizing current evidence, this review provides a decision-making algorithm to guide optimal device selection and improve safety outcomes in this vulnerable pediatric population.

Introduction

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For anesthesiologists, managing one-lung ventilation (OLV) in children poses significantly greater challenges than in adults. As minimally invasive thoracoscopic and robotic surgical techniques continue to evolve and expand, the demand for OLV in pediatric thoracic surgery is increasing. In parallel, advances in the understanding of pediatric physiology and lower respiratory tract anatomy, along with the development of bronchial blocking devices and related technologies, have contributed to progress in pediatric lung isolation.

Under physiological conditions, the human body maintains a homeostatic balance between ventilation and perfusion (....

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Protocol

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Pediatric lung isolation techniques
Although double-lumen tubes (DLTs) serve as the definitive benchmark for one-lung ventilation (OLV) in adult thoracic surgery, pediatric lung isolation lacks a universally accepted gold standard9. Current practice relies on a tailored selection of single-lumen endotracheal tubes (SLTs), DLTs, or bronchial blockers (BBs), depending on the patient’s age and anatomy10 (Table 1).

Device CategoryDevi....

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Results

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The management of one-lung ventilation (OLV) in pediatric patients remains one of the most demanding tasks in modern anesthesiology and is fundamentally distinct from adult practice due to unique physiological and anatomical constraints. This review highlights that, despite increasing demand for pediatric thoracic surgery, a unified “gold standard” for lung isolation remains elusive. Device selection is dictated by age and airway dimensions: while double-lumen tubes (DLTs) provide optimal isolation in older c.......

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Disclosures

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The authors declare no conflict of interest.

Acknowledgements

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This work was supported by Capital’s Funds for Health Improvement and Research (No. 2022-2Z-2098 to Xin Zhao), Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support (No. XMLX202145 to Xin Zhao), the Beijing Municipal Science & Technology Commission Proof of Concept Platforms (No. 2024030119), and the Beijing Municipal Science & Technology Commission Technology Transfer Office (No. 20250481320).

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Tags

Pediatric Lung IsolationDouble Lumen TubesBronchial BlockersSingle Lumen TubesLung Protective VentilationFiberoptic VerificationHypoxemia ManagementThoracic Surgery Pediatrics3D Printed Blockers

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