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TOPICAL COLLECTIONS

Human Mycoplasma/Ureaplasma: From Discovery to the Future

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Dr. Prenilla Naidu

Dr. Prenilla Naidu

Provincial Laboratory for Public Health and the Department of Laboratory Medicine and Pathology at the University of Alberta

Dr. Prenilla Naidu is a Medical Microbiologist at the Provincial Laboratory for Public Health in Alberta, Canada, and an Assistant Clinical Professor in the Department of Laboratory Medicine and Pathology at the University of Alberta. She received her MD from Natal University, in South Africa and subsequently trained and worked in Paediatrics in South Africa and the United Kingdom. Since her arrival in Canada in 1999, she worked in general practice, as a consultant at the STI Clinic and at the inner-city Health Centre in Edmonton, before obtaining her Royal College of Physicians and Surgeons of Canada qualifications in Medical Microbiology and Diploma in Tropical Medicine and Hygiene from the University of Glasgow, UK. Her research interests in sexually transmitted infections (STI) started in 1998 during her first medical microbiology residency in South Africa when she managed an STI clinic in a rural village and conducted research studies to direct the National STI Treatment Guidelines. She continues her research in this area with ongoing projects, locally, nationally and international collaborations, on syphilis, chlamydia, gonorrhea, mycoplasma and trichomonas infections. She was the STI lead at the Provincial Laboratory and served in numerous leadership roles. She has participated in the development of various infectious disease treatment and diagnostic guidelines at provincial and national levels and, currently, as co-chair of the national Canadian Public Health Laboratory Network Syphilis Diagnostic Working Group, is involved in updating the national syphilis testing and diagnostic guidelines. She is also integrally involved in the Medical Microbiology Residency Training Program at the University of Alberta.  

Collection Overview

The family Mycoplasmataceae includes bacteria from the genera Mycoplasma and Ureaplasma. They are unique in that they permanently lack a cell wall. These organisms can colonize human respiratory and genital tracts and under certain conditions, can cause infections. Their tiny genome and resultant limited biosynthetic capabilities make them extremely fastidious and difficult to culture and detect in clinical laboratories. There was thus, little known about them until the recent development and evolution of molecular detection techniques. From de novo infections of the respiratory tract (M. pneunomiae) and sexually transmitted M. genitalium infections, to opportunistic infections in the immunocompromised, these organisms are gaining more attention from the medical and scientific communities. 

This collection explores the different techniques available and in development, for culture, identification, and antimicrobial resistance detection for this family of organisms.

Articles

Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of <em>Mycoplasma pneumoniae</em>
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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae

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2023

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