
Andreas Walter
Aalen University, Centre of Optical Technologies, Aalen, Germany
Prof. Dr. Andreas Walter studied physics and biophysics at the University of Heidelberg on a Baden-Wuerttemberg Scholarship. He spent his research career developing and applying various imaging techniques for life sciences. After his tenure as a guest scientist at the European Molecular Biology Laboratory, he did his PhD at the Max Planck Institute of Biophysics on method development in cryo-electron microscopy. He finished his studies with distinction. He continued his research in imaging and worked as a postdoc and DFG fellow at the University of California San Francisco and at the Lawrence Berkeley National Laboratory to correlate soft x-ray tomography and cryo-light microscopy. He is also a fellow of the German Scholars Organization. Prof. Dr. Walter was appointed Director of Austrian BioImaging in October 2016, and he is now Professor of Biophotonics and Bioimaging at Aalen University, Germany, at the Centre for Optical Technologies. He is also the main proposer and Chair of the EU-funded COST Action COMULIS (www.comulis.eu).

Julia Fernandez-Rodriguez
University of Gothenburg, Shalgrenska Academy, Centre for Cellular Imaging
Julia Fernandez-Rodriguez is the Head of the Centre for the Cellular Imaging University of Gothenburg, Node of the Swedish National Microscopy Infrastructure (NMI), Vice-chair of the Panels of Node Board for the Euro-BioImaging ERIC consortium and President of the Core Technologies for Life Sciences Association (CTLS). She graduated (1989) in Biology from the University Santiago de Compostela (Spain) and received her PhD (1996) in Biochemistry from the University of Vigo (Spain). She has a background in Cell and Molecular Biology. She is responsible for an open-access Correlative Multimodal Imaging Facility that provides technical and scientific excellence by integrating multiple imaging technologies, which currently totals 15 microscopy-based imaging systems, together with image processing and analysis tools in a single core. The main interest is to provide expertise in correlated multimodal imaging workflows, from experimental design to image acquisition and analysis, tailored to various research domains within the Life Sciences. She has more than 20 years of experience in the organisation, implementation and management of core facilities and training activities at the National and International levels. Furthermore, she has supervised core internship and ERASMUS students in bioimaging, promoting future career possibilities and introducing core facility work as a possible career direction. She is the scientific coordinator of the NMI member of the Main Board of the Nordic Microscopy Society (SCANDEM) and the Bridging Nordic Microscopy Infrastructure (NordForks). On the European landscape, she is also well connected to several other European facilities through the European Light Microscopy Initiative, ELMI (member of the Steering committee). Further, she represents Sweden on the Management Committee. She is the Coordinator of the Short-Term Scientific Missions of 2 European COST Actions: NEUBIAS (CA15124) -network of Bioimage Analysts; and COMULIS (CA17121) -network in Correlated Multimodal Imaging in Life Sciences. Among her responsibilities, she has been vital in recruiting the next generation of microscopists to fulfil the long-term goals of the CCI and the University of Gothenburg.
Biomedical research aims at gaining a mechanistic diseases understanding and entire organisms across scales. One approach to achieve this goal is Correlative Multimodal Imaging (CMI), which combines complementary modalities to gain holistic structural, functional, and chemical information about the entire sample and place molecular details into their overall spatio-temporal multiscale context. CMI correlates two or more imaging modalities and creates a zoomable and composite view of the specimen and region of interest. There are two prominent examples in biological research (Correlated Light and Electron Microscopy, CLEM) and preclinical and clinical research (hardware-fused hybrid imaging setups, such as Computed Tomography/ Positron Emission Tomography, PET/CT). While the frontiers of bioimaging are currently being pushed towards integrating several modalities to tackle biomedical research questions holistically and across multiple scales, the development of advanced implementations is still in its infancy. Specifically, CMI approaches that bridge in vivo and ex vivo imaging beyond CLEM and hybrid imaging is lacking – despite their great potential for research and diagnostics.
In this context, it is of great interest to highlight these efforts in a dedicated collection, present quality standards for existing CMI approaches and commonly accepted protocols, and showcase novel CMI pipelines across scales and their potential to tackle exciting biomedical research questions. This edition will specifically highlight approaches to bridge the gap between preclinical (such as PET/CT) and biological (CLEM) imaging and promote corresponding correlation software and open databases.
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Cited by 3
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2023
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Mirko Thamm1,2, Justin J. Jeffery3, Yapei Zhang4, Bryan R. Smith4, Stephen Marchant5, Fabian Kiessling1,6, Felix Gremse1,2
1Institute for Experimental Molecular Imaging, RWTH Aachen University, 2Gremse-IT GmbH, 3Carbone Cancer Center, University of Wisconsin, 4Department of Biomedical Engineering and Institute for Quantitative Health Science and Engineering, Michigan State University, 5MediLumine Inc., 6Fraunhofer Institute for Digital Medicine MEVIS