Guest Editor
Collection Overview
This Methods Collection focuses on creating animal models using surgical approaches in biomedical research. Significant progress has been made in the field of surgical animal models, leading to numerous publications. However, to enhance reproducibility and accessibility, video-based publications are proposed for several of these complex programs. By providing detailed visual demonstrations, other researchers worldwide can easily replicate these techniques, addressing concerns related to the reproducibility crisis in pre-clinical biomedical research.
The collection will specifically cover complex procedures such as:
1. Thoracic vertebral laminectomy for spinal cord injury in rats using a motorized approach.
2. Thoracotomy in rats.
3. Coronary ligation.
4. Implantation of electrodes in the skull.
5. Sleep research in rats.
6. Other related works, including the surgical induction of parkinsonism.
Despite previous publications on these techniques, their novelty and complexity will attract considerable interest from researchers seeking to view and replicate them. The goal is to contribute to the scientific community's knowledge base by providing comprehensive and accessible resources for advancing pre-clinical research.
Articles
Abstracts
A detailed protocol for estimating the minimum alveolar concentration of sevoflurane in rat model
Roxana Polojintef-Corbu*1
1Medical University of Vienna, Department of Anaesthesia, Intensive Care Medicine and Pain Medicine, Clinical Division of General Anaesthesia and Intensive Care Medicine, Vienna, Austria