Guest Editors
Daniel Junqueira Dorta
University of São Paulo
Daniel Dorta is a toxicology and clinical chemistry professor at the University of São Paulo, Brazil. Dr. Dorta graduated in pharmacy and biochemistry, specializing in clinical pharmacology. He has a PhD in toxicology, a Master's in pharmaceutical sciences, and a post-doctorate in pharmacology. He is a past president of the Brazilian Society of Toxicology and the Brazilian Society of Forensic Sciences. He was also a director of the Executive Committee of the International Union of Toxicology. He has written more than 60 articles and 17 book chapters. He is co-editor and author of Forensic Toxicology (in Portuguese), Toxicity Assessment – Methods and Protocols and The Toxicity of Environmental Pollutants. He has experience in the toxicological evaluation of ingredients applied to the pharmaceutical industry and PDE/ADE determinations.
Danielle Palma de Oliveira
University of São Paulo
Danielle Palma de Oliveira graduated in pharmacy and biochemistry from the School of Pharmacy and Dentistry of Alfenas. She has a Master’s and PhD in toxicology and toxicological analysis. She is an associate professor at the Faculty of Pharmaceutical Sciences of Ribeirão Preto. She is a past president of the Brazilian Society of Toxicology and coordinator of the Environmental Toxicology Laboratory. She is the author of more than 60 articles and 15 book chapters. She is one of the editors and authors of Toxicity Assessment – Methods and Protocols. She has 20 years of experience in toxicology, in the toxicological evaluation of ingredients applied to the pharmaceutical industry, and in PDE/ADE determinations according to ICH guidelines.
Collection Overview
This Methods Collection aims to showcase innovative approaches that depart from traditional methods, promoting ethical, efficient, and sustainable research in toxicology. It includes a range of protocols for assessing the toxic effects induced by different chemical compounds. Contemporary approaches employing alternative models that eliminate the need for animal testing are emphasized.
Conventional toxicological analysis typically depends on animal models. This Methods Collection focuses on various alternatives, including in vitro models, omics technologies, and advanced sensors, in alignment with the principles of the 3Rs (Replacement, Reduction, and Refinement).
