Metabolic diseases, including conditions such as obesity, diabetes, and metabolic syndrome, pose a significant global health challenge. Metabolic mechanisms are fundamental to an organism's ability to extract energy from nutrients, synthesize essential molecules, and maintain metabolic homeostasis. Identifying and quantifying these mechanisms is essential for localizing perturbations in patients and leveraging findings to address these health challenges. Metabolic mechanism research involves various methods and techniques to study and understand the intricate biochemical and molecular processes that underlie metabolism. 

This collection will encompass a range of metabolic mechanism methods, including metabolic flux analysis using stable isotope tracers, lipidomics, single-cell metabolomics, NMR spectroscopy, electron paramagnetic resonance (EPR), organoids and 3D cultures, metabolic super-resolution microscopy, in vivo metabolic imaging, genome editing for metabolic pathway manipulation, real-time metabolite monitoring, organ-on-a-chip models, and chemoproteomic approaches.