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TOPICAL COLLECTIONS

Current methods in neuromodulation and brain-computer interfaces
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Guest Editor

Ryan Neely

Ryan Neely

Elemind Technologies, Inc.

Ryan Neely is the Vice President of Science and Research at Elemind Technologies, Inc., where he is developing non-invasive neuromodulation systems and techniques. Ryan received his Ph.D. from the University of California, Berkeley in 2017, where he researched wireless neural interfaces and the neural dynamics of neuroprosthetic learning under the supervision of Dr. Jose Carmena. Ryan has held director-level positions at iota Biosciences, Inc., a company developing wireless neural interfaces, and at Known Medicine Inc., where he worked on high-throughput organoid screening technology. 

Collection Overview

Neurotechnology for interfacing with the brain is advancing at a rapid pace. There is a growing body of both proprietary and open-source solutions for modulating and/or decoding neural activity that has seen adoption by academic researchers, hobbyist communities, and for-profit organizations. However, implementing and troubleshooting neural interfaces still requires an understanding of neurobiology, electrical engineering, computer science, and materials engineering. The goal of this collection is to provide a detailed understanding of how the hardware, software, and biology of neural interfaces combine to successfully enable neuromodulation and/or neural decoding. Readers of this collection will be able to gain deeper knowledge of current methods and systems for stimulating and modulating neural activity using invasive, non-invasive, animal, and human models. In addition to focusing on the physical interface between electronics and the brain, this collection will also include methods for interpreting and processing signals collected by neural interfaces as well as strategies for tuning parameters of neurostimulation.

Articles

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
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Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat

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2025

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Abstracts

Concurrent Temporal Interference Stimulation with EEG in Humans

Thomas Deegan*1,

Edward Rhodes*1,

Ketevan Alania1,

Nir Grossman*1

1Imperial College London