Chronic wounds, particularly plantar ulcers in leprosy patients, remain a major challenge globally due to impaired nerve function, delayed healing, and limited access to effective treatments. Recent advancements in regenerative medicine, such as the application of stem cell-derived products, novel topical agents, and biologically active dressings, have opened new therapeutic pathways to accelerate wound healing.
This collection aims to bring together diverse methodologies and research innovations in chronic wound care, focusing not only on leprosy-associated ulcers but also on other neuropathic wounds, such as diabetic foot ulcers and pressure sores. We welcome submissions that explore new wound dressing protocols, stem cell applications (including conditioned media), skin grafting techniques, and digital wound assessment tools.
This Methods Collection serves as a platform for clinicians, researchers, and biomedical scientists worldwide to share techniques and results that can improve wound management practices and patient outcomes.
Autologous Platelet-Rich Fibrin (PRF) as an Effective Low-Cost Therapy for Non-Healing Plantar Ulcers in Leprosy Patients
Flavio Alves Lara1,
Sinesio Talhari*2,
Amanda Gabrielle dos Santos Cordeiro2,
Maria Cecilia Augusto Porto3,
Jaqueline da Silva Mendes3,
Thiago Montenegro da Silva3
1Fiocruz Foundation, Rio de Janeiro, Brasil,
2Fundação Hospitalar Alfredo da Matta (FUHAM),
3Fundação Hospitalar Alfredo da Matta