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TOPICAL COLLECTIONS

Characterizing Polymicrobial Biofilms and Their Metabolomics

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Guest Editor

Jagir Hussan

Jagir Hussan

University of Auckland, Auckland Bioengineering Institute

Jagir Hussan is a bioengineer with 15 years of experience in human physiology and complex systems research. His research work spans across the basic science and applied biomedical discovery spectrum. He works closely with industry and maintains strong linkages with diverse research groups, globally. He has significant expertise in both the development and integration of experiments, instrumentation, and computer modelling to unravel complex relationships. Currently, he leads the Animal and Microbiome group at the Auckland Bioengineering Institute, University of Auckland, New Zealand. The group is interested in developing biotechnological solutions to modulate host-microbiome interactions. Their investigations center on how the host-microbiome interaction architecture evolves, potentiates, and modulates the activation of mechanical, chemical, and electrical signaling pathways and control programs. A targeted outcome is to determine the mechanisms underlying disease phenotypes, farm productivity, pollution, and green-house gas mitigation.

Collection Overview

Much of the bacteria in the biosphere occur as biofilms, a state that enables them to protect themselves and often renders antibiotics that are potent against their planktonic counterparts ineffective. Humans have co-evolved with biofilms over millennia to optimally exploit the environment and provide niches that host biofilms. Often, this interaction is commensal, but a biofilm in the wrong place can lead to potentially fatal consequences. Unravelling this intricate host-biofilm relationship is necessary to develop biotechnologies to treat diseases and advance quality of life. This requires the development of cutting-edge techniques to handle such complexity.

This collection brings together methods to analyze, cultivate, and characterize biofilms, along with methods to determine their response to neuroendocrine chemicals and therapeutics under in-vivo and in-vitro conditions.

Articles

Generation of Greater Bacterial Biofilm Biomass using PCR-Plate Deep Well Microplate Devices
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Generation of Greater Bacterial Biofilm Biomass using PCR-Plate Deep Well Microplate Devices

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Cited by 2

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2022

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Abstracts

GROWTH AND TREATMENT OF ORAL POLYMICROBIAL BIOFILMS INVOLVED IN THE ONSET OF PERIODONTITIS

Joel Weadge*1

1Wilfrid Laurier University

Methodologies for studying complex interactions in polymicrobial biofilms formed by Acinetobacter baumannii and Candida albicans

K Prashanth*1

1Pondicherry University