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TOPICAL COLLECTIONS

Methods Employed for Wound Healing: Mechanisms and Treatment Modalities

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Surendra Nimesh

Surendra Nimesh

Central University of Rajasthan, Department of Biotechnology, School of Life Sciences

Dr. Surendra Nimesh obtained his MSc degree in Biomedical Science and PhD degree in Nanotechnology from Dr. B.R. Ambedkar Center for Biomedical Research, University of Delhi and CSIR - Institute of Genomics and Integrative Biology, Delhi, India. He is presently working as UGC Assistant Professor in the Department of Biotechnology, at Central University of Rajasthan, India. He has authored several research and review articles in international peer reviewed journals, as well as book chapters and five books. He worked as postdoctoral fellow at Ecole Polyetchnique of Montreal, Clinical Research Institute of Montreal, McGill University, and Visiting Fellow at Health Canada from 2007- 2013. His area of interest is nanotechnology for drug, gene, and siRNA delivery for the treatment of cardiovascular diseases and breast cancer. He is currently investigating the antimicrobial and antibiofilm potential of biosynthesized silver nanoparticles using various plant extracts. One of the domains that he is working in is to employ silver nanoparticles in wound healing studies in in vivo models.

Collection Overview

A wound is a break or defect in the skin that is caused by physical or thermal damage. Wound repair is a well-orchestrated multi-step process that initiates with homeostasis, followed by inflammation of the wounded region that facilities tissue proliferation, ultimately culminating in tissue remodeling. Wounds are categorized into two types based on healing time. Acute wounds are exemplified by tissue damage that is usually repaired within 8-12 weeks with minimal scarring, while healing in chronic wounds extends beyond 12 weeks. Though a plethora of wound dressing materials have been developed, the problem of wound management still stands tall. The foremost challenge in wound treatment is the promotion of wound healing along with the prevention of bacterial infection.

This Methods Collection is dedicated to strategies employed for deciphering the underlying mechanisms of the wound healing and skin repair process. A better understanding of this mechanism is needed as it would empower researchers to accelerate the wound healing process. This collection will also emphasize both conventional and modern strategies to facilitate wound healing including wound dressings, use of antibiotics, ultrasound and electromagnetic therapy, nanomedicine, and skin grafts.

Articles

Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair
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Human Ex vivo Wound Model and Whole-Mount Staining Approach to Accurately Evaluate Skin Repair

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Cited by 17

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2021

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