Flora Meilleur

Flora Meilleur photo

Affiliation: North Carolina State University and Oak Ridge National Laboratory

Dr. Meilleur is a structural biologist specializing in protein chemistry and neutron crystallography, in the Department of Molecular and Structural Biochemistry, NC State, Raleigh and in Neutron Scattering Division, Oak Ridge National Laboratory (ORNL), Oak Ridge. Dr. Meilleur received her PhD in biophysics from the European Molecular Biology Laboratory (EMBL) and Université Grenoble Alpes (Grenoble, France) in 2004. She then served as an instrument scientist on the LADI diffractometer at the Institut Laue Langevin (ILL), Grenoble. She moved to ORNL in 2005 and has held a joint faculty appointment with the Biochemistry department of NC State University since 2007.  At ORNL’s High Flux Isotope Reactor she delivered the single-crystal diffractometer instrument IMAGINE. She currently supports and collaborates with users to elucidate enzymatic mechanisms using IMAGINE and the MaNDI instrument at ORNL’s Neutron Spallation Source. Her own research focuses on redox enzymes including the recently discovered lytic polysaccharide monooxygenases. She combines small angle X-ray/neutron scattering, X-ray/neutron crystallography, DFT calculations and isotopic labeling techniques to study the structure, function, and dynamics of these systems.