Affiliation: Department of Psychiatry, Icahn School of Medicine at Mount Sinai

Dr. Swadha Singh is an assistant scientist in the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai, New York. She earned her PhD and master’s in quantitative and systems biology from the University of California, Merced (2017–2022), and her MSc (2012–2014) and BSc (2009–2012) degrees in bioinformatics and applied science from the University of Allahabad, India. Her research integrates computational biology, single-cell transcriptomics, and epigenomics to uncover molecular mechanisms underlying neuropsychiatric disorders such as schizophrenia and bipolar disorder. She developed the first large-scale cell-type-specific genomic and 3D chromatin architecture resource from human midbrain dopaminergic neurons. In parallel, she has developed an integrative multi-omic framework combining CAGE-seq promoter entropy, ATAC-seq, and RNA-seq to dissect promoter activity, chromatin accessibility, and transcriptional regulation in the human brain, providing insight into disease-associated promoter switching and transcription factor dynamics. She has authored multiple research publications spanning computational genomics, chromatin biology, and transcriptomic regulation. Dr. Singh is a member of the PsychENCODE Consortium, the Society for Neuroscience, and the American Society of Human Genetics.