Hydrophilic Polymer

Hydrophilic polymers are macromolecules containing polar or charged groups that interact strongly with water, making them useful for controlling hydration, solubility, and molecular transport in biochemical systems. Their functional groups form hydrogen bonds or electrostatic interactions with water; when polymer chains are cross-linked, these interactions drive swelling and produce hydrated networks known as hydrogels, while uncross-linked chains may dissolve. In biochemistry, hydrophilic polymers support biomolecule immobilization, cell-compatible coatings, separation methods, and controlled delivery of proteins or other therapeutic molecules. Their composition, chain architecture, and cross-linking density determine water uptake, mechanical behavior, and diffusion, enabling materials tailored for research and biomedical applications.

Hydrophilic Polymer - Related Videos

Research

JoVE EoE - Chromatography Techniques

Hydrophilic Interaction Liquid Chromatography: A Technique to Separate Hydrophilic Polar Analytes Using Hydrophilic Beads

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2025

This video demonstrates the principle of separation of hydrophilic polar compounds using hydrophilic interaction liquid chromatography. This technique helps in the purification of various polar analytes, including N-glycans.

A Protocol for the Production of Gliadin-cyanoacrylate Nanoparticles for Hydrophilic Coating

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2016

This article presents a protocol for the production of protein-based nanoparticles that changes the hydrophobic surface to hydrophilic. The produced nanoparticle is an assembly of gliadin-cyanoacrylate diblock copolymers. Spray coating with the produced nanoparticle changes the surface of target material to a hydrophilic surface.

Education

JoVE Core - Chemistry

Polymers

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2020

The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the properties that they exhibit. Additionally,...

Tension Tests of Polymers

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2023

Source: Roberto Leon, Department of Civil and Environmental Engineering, Virginia Tech, Blacksburg, VA Polymeric materials are widely used in civil structures, with uses ranging from very soft sealants to more rigid pipes in water and wastewater systems. The most basic definition of a polymer is a molecular structure with repeating subunits. The term polymer comes from Greek, where "poly" means many, and "-mer" means basic unit. Monomers, or single mers, are the specific repeating units. With...

Research

JoVE Journal - Bioengineering
Free Sample

Polymer Microarrays for High Throughput Discovery of Biomaterials

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Cited by 32 •

2012

A description of the formation of a polymer microarray using an on-chip photopolymerization technique. The high throughput surface characterization using atomic force microscopy, water contact angle measurements, X-ray photoelectron spectroscopy and time of flight secondary ion mass spectrometry and a cell attachment assay is also described.

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