Handheld System

A handheld system is a compact, portable instrument that integrates sensing, signal processing, and user output in a device designed for operation outside a conventional laboratory. In bioengineering, miniaturized sensors capture biological or physical signals, while embedded electronics convert, analyze, and display measurements in near real time. These systems support point-of-care diagnostics, physiological monitoring, field-based measurements, and rapid assessment of biological samples, often reducing reliance on centralized equipment. Their portability can improve access to testing and enable measurements in clinical, environmental, and resource-limited settings, while continued advances in microfabrication and low-power electronics expand their analytical capabilities.

Handheld System - Related Videos

Research

JoVE Journal - Bioengineering

Handheld Device for Saliva Pretreatment to Improve Cortisol Detection

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2026

This protocol describes a rapid saliva pretreatment method for improving cortisol detection. A handheld filtration device is used to remove mucins and other interfering substances while preserving the target analyte. The pretreated saliva exhibits improved capillary flow, thereby enabling more consistent and reproducible assay performance.

Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer

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Cited by 2 •

2020

Simple and accessible methods were developed to measure the motor aspect of cancer-related fatigue objectively and quantitatively. We describe, in detail, ways to administer the physical fatigue test using a simple handgrip device as well as methods to calculate fatigue indices.

Research

JoVE Journal - Cancer Research
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Manual Construction of a Tissue Microarray using the Tape Method and a Handheld Microarrayer

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Cited by 5 •

2022

This protocol outlines the tape method on how to manually construct a tissue microarray using FFPE donor blocks of differing depths.

Handheld Metal Detector Screening for Metallic Foreign Body Ingestion in Children

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Cited by 5 •

2018

Here, we present a protocol to use the handheld metal detector, to screen for the presence of ingested metallic foreign bodies in children who present to the pediatric emergency medicine department with a history of foreign body ingestion.

Measurement of Aerosols Optical Thickness of the Atmosphere using the GLOBE Handheld Sun Photometer

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Cited by 4 •

2019

The goal of the methods presented here is to measure aerosol optical thickness of the atmosphere. The sun photometer is pointed at the sun and the largest voltage reading obtained on an in-built digital voltmeter is recorded. Atmospheric measurements such as barometric pressure and relative humidity are also performed.

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