Autonomic Regulation

Autonomic regulation is the biological control of involuntary functions that maintain internal stability, including heart rate, blood pressure, digestion, breathing, and body temperature. In the nervous system, the hypothalamus and brainstem integrate sensory information and adjust activity through autonomic reflexes, primarily using the sympathetic and parasympathetic divisions; neurotransmitters such as acetylcholine and norepinephrine act on target organs to produce coordinated responses. This regulation enables rapid adaptation to stress, rest, feeding, and environmental change while supporting homeostasis. Studying autonomic regulation helps explain cardiovascular and gastrointestinal function and provides a foundation for understanding disorders involving dysautonomia, stress responses, and neural control of organ systems.

Autonomic Regulation - Related Videos

Research

JoVE Journal - Medicine
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Quantitative Autonomic Testing

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Cited by 179 •

2011

Standardized, comprehensive and fully quantitative testing of autonomic functions is described. The autonomic tests consist of evaluation of all three major autonomic domains including cardiovagal, adrenergic and sudomotor. The severity and distribution of dysautonomia is quantitated using Composite Autonomic Severity Scores.

Research

JoVE EoE - Neuropathology

Developing a Translaminar Pressure Model Using a Translaminar Autonomous System

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2025

Source: Sharma, T. P., et al., Translaminar Autonomous System Model for the Modulation of Intraocular and Intracranial Pressure in Human Donor Posterior Segments. J. Vis. Exp. (2020).This video demonstrates the procedure of preparing a human eye to study the effects of translaminar pressure on retinal ganglion cell signaling by simulating intraocular and intracranial pressures in a translaminar autonomous system.

Education

JoVE Core - Anatomy and Physiology

Autonomic Nervous System

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2025

The autonomic nervous system (ANS) is a critical component of the peripheral nervous system, primarily responsible for regulating involuntary bodily functions and maintaining homeostasis. It functions in tandem with the central nervous system (CNS) to seamlessly coordinate various physiological processes without the need for conscious control. The ANS comprises two main divisions: the sympathetic and parasympathetic divisions. These divisions function antagonistically to maintain a dynamic...

Research

JoVE Journal - Medicine
Free Sample

Measuring Cardiac Autonomic Nervous System (ANS) Activity in Children

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Cited by 37 •

2013

Measurement of autonomic nervous system activity usually confines the researcher and participant to the laboratory, which may provide an intimidating environment to children. The VU University Ambulatory Monitoring System (VU-AMS) device can record cardiac autonomic control in any setting. The VU-AMS proved very amenable to testing in children.

Disorders of the Autonomic Nervous System

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2024

The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body. Raynaud's disease, also known as Raynaud's phenomenon, is a...

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