Clip Placement

Clip placement is the controlled positioning of a small mechanical clip on a biological specimen, tissue, vessel, or experimental setup to secure, mark, isolate, or temporarily compress a target. The procedure relies on accurate anatomical or spatial alignment and calibrated mechanical force, allowing the clip to remain stable without causing unintended damage or disrupting nearby structures. In biology, clip placement supports surgical models, tissue manipulation, specimen preparation, and laboratory workflows that require reproducible control of a defined site. Consistent placement improves experimental precision, facilitates observation of biological responses, and helps standardize procedures across samples and studies.

Clip Placement - Related Videos

Education

JoVE Science Education - Clinical Skills

Arterial Line Placement

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2023

Source: Sharon Bord, MD, Department of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA When monitoring patients, it is important to obtain values that are accurate and reliable. Blood pressure monitoring is one of the essential vital signs, and for a majority of patients, measuring it utilizing non-invasive techniques provides accurate values. However, there are situations in which the blood pressure requires more exact, specific, and reliable measurements.

Intraosseous Needle Placement

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2023

Source: Julianna Jung, MD, FACEP, Associate Professor of Emergency Medicine, The Johns Hopkins University School of Medicine, Maryland, USA For unstable patients requiring urgent administration of medications, fluids, or blood products, establishing vascular access quickly is essential. However, there are many factors that can complicate placement of a peripheral intravenous cannula (PIV), and it is extremely common for PIV attempts to fail. PIV placement may be technically challenging in small...

Research

JoVE EoE - Danio rerio (zebrafish)

DNA Extraction from Tail Clip: A Method Used in Zebrafish Genotyping

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2023

This article describes DNA extraction from zebrafish tail clip. The protocol demonstrates a rapid and efficient method to analyze zebrafish genotypes.

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

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Cited by 3 •

2009

Description of the surgical obliteration of a cerebral aneurysm utilizing an ultrasonic flow probe to assess arterial flow prior to and after aneurysm clip placement.

Sleeve Gastrectomy in Mice using Surgical Clips

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Cited by 2 •

2020

The prevalence of diabetes and obesity is continuously increasing worldwide. The mechanisms between diabetes, obesity and their associated mortality and co-morbidities need to be further investigated. Here, we present a protocol for sleeve gastrectomy (SG) in animals as an uncomplicated preclinical model of bariatric surgery.

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