Hypotonic Sweat

Hypotonic sweat is sweat with a lower concentration of dissolved solutes than blood plasma, a characteristic that helps the body regulate temperature without losing equivalent amounts of electrolytes and water. Eccrine sweat glands release a fluid resembling plasma, but as it moves through the gland ducts, sodium and chloride are reabsorbed more efficiently than water, producing a dilute secretion at the skin surface; the degree of hypotonicity varies with sweat rate and ductal transport. In biology, studying hypotonic sweat clarifies thermoregulation, fluid balance, and electrolyte physiology, while helping explain how prolonged exercise, heat exposure, hydration status, and individual gland function influence salt loss and performance.

Hypotonic Sweat - Related Videos

Education

JoVE Core - Anatomy and Physiology

Accessory Structures of the Skin: Sweat Glands

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2023

Sweat glands or sudoriferous glands are one of the important accessory structures of the skin. They are small, coiled tubular structures located in the dermis, the middle layer of the skin. Sweat glands are responsible for producing and secreting sweat, a watery fluid that helps regulate body temperature and excrete waste products. Sweat glands are classified as merocrine glands; that is, the secretions are excreted by exocytosis through a duct without affecting the cells of the gland. There...

Research

JoVE Journal - Biology

Retinal Cryo-sections, Whole-Mounts, and Hypotonic Isolated Vasculature Preparations for Immunohistochemical Visualization of Microvascular Pericytes

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Cited by 2 •

2018

We demonstrate three different tissue preparation techniques for immunohistochemical visualization of rat retinal microvascular pericytes, i.e., cryo-sections, whole-mounts, and hypotonic isolation of the vascular network.

Research

JoVE Journal - Medicine
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Quantitative Autonomic Testing

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Cited by 176 •

2011

Standardized, comprehensive and fully quantitative testing of autonomic functions is described. The autonomic tests consist of evaluation of all three major autonomic domains including cardiovagal, adrenergic and sudomotor. The severity and distribution of dysautonomia is quantitated using Composite Autonomic Severity Scores.

Operative Technique and Nuances for the Stereoelectroencephalographic (SEEG) Methodology Utilizing a Robotic Stereotactic Guidance System

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Cited by 1 •

2023

The SEEG methodology is simplified and made faster with a stereotactic robot. Careful attention must be paid to the registration of the preoperative volumetric MRI to the patient prior to use of the robot in the OR. The robot streamlines the procedure, leading to decreased operative times and accurate implantations.

Measurement of 3-Dimensional cAMP Distributions in Living Cells using 4-Dimensional (x, y, z, and λ) Hyperspectral FRET Imaging and Analysis

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Cited by 6 •

2020

Due to inherent low signal-to-noise ratio (SNR) of Fӧrster resonance energy transfer (FRET) based sensors, measurement of cAMP signals has been challenging, especially in three spatial dimensions. Here, we describe a hyperspectral FRET imaging and analysis methodology that allows measurement of cAMP distribution in three spatial dimensions.

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