Left Atrium Cannulation
Left Atrium Cannulation - Related Videos
08:17
Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
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Cited by 8 •
2017
The following protocol describes the methodology for the acquisition and analysis of echocardiographic images used to obtain the Left Atrial Volume (LAV), Aorta (Ao) diameter, and Pulmonary Artery (PA) diameter in mice. This technique is a non-invasive, non-terminal procedure that allows assessment of the cardiopulmonary function.
04:29
Three-Dimensional Modeling of the Left Atrium and Pulmonary Veins with a Precise Intracardiac Echocardiography Approach
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2023
Accurate intracardiac echocardiography (ICE) shows significant accuracy in estimating the left atrial structure, a prospective and promising cardiac structure estimation method. Here we propose a protocol for three-dimensional modeling of the left atrium and pulmonary veins with ICE and fast anatomical mapping (FAM) catheter remodeling.
07:39
Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
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Cited by 1 •
2021
The following article describes the stepwise procedure for placement of a device (e.g., Tandemheart) in cardiogenic shock (CS) that is a percutaneous left ventricular assist device (pLVAD) and a left atrial to femoral artery bypass (LAFAB) system that bypasses and supports the left ventricle (LV) in CS.
04:28
Cannulation of the Carotid Artery in a Rat Model
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2025
In this video, we demonstrate a surgical procedure to cannulate the left carotid artery in a rat model.
02:05
Intraduodenal Cannulation in a Rat Model for Immunopathology Studies
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2025
This video demonstrates intraduodenal cannulation in a rat model. After anesthetizing the rat, the duodenum is located and a small puncture is created. A J-shaped cannula with a beveled tip is carefully inserted and secured, and the incision is closed. The cannulated rat model enables intra-intestinal infusion for immunopathology studies.
FAQs
Two access strategies are identified: surgical entry through a pulmonary vein and a transseptal route. Both establish a pathway to the left atrium, but they represent different anatomical approaches to creating that connection. The selected route is therefore part of experimental design, especially when investigators need controlled access while preserving blood flow and limiting leakage.
Catheter stabilization is central to reliable cannulation. A secured catheter maintains a stable connection during pressure measurement, fluid delivery, or fluid collection, while the surrounding circulation continues to support blood flow. Minimizing leakage matters because uncontrolled loss could compromise the connection and reduce the consistency of samples, infusions, or hemodynamic observations.
The technique can support direct pressure measurements and controlled blood sampling or fluid exchange at the left atrium. In cardiovascular biology, these capabilities connect local atrial conditions with broader questions about cardiac function, pulmonary venous return, and blood oxygenation. Its value lies in linking an accessible experimental interface to measurable cardiovascular processes.
After an access route is established, the catheter is placed into the left atrium and secured to maintain a stable connection. Investigators can then measure pressure, deliver fluids, or collect samples under controlled conditions. Throughout the setup, preserving blood flow and minimizing leakage are important procedural objectives because they help maintain the intended experimental environment.
Left atrium cannulation provides an experimental point for examining pressures and flow-related cardiovascular behavior. By combining pressure measurements with access to left-atrial blood, investigators can study cardiac function and pulmonary venous return under controlled conditions. The same setup can also contribute to blood-oxygenation studies, extending its use beyond structural access alone.
Experimental animal models can use the cannulated connection for controlled sampling or infusion while cardiovascular variables are studied. This arrangement allows researchers to collect blood or introduce fluids in a defined setting. It is particularly relevant when an experiment examines cardiac function, pulmonary venous return, hemodynamics, or blood oxygenation.