Mid-range Inhomogeneity

Mid-range inhomogeneity describes spatial variation in a biological system at an intermediate scale, between fine molecular fluctuations and differences across an entire tissue or organism. It arises when cells, extracellular components, biochemical signals, or physical properties form locally distinct regions rather than distributing uniformly. These patterns can influence diffusion, cell-cell communication, mechanical behavior, and responses to environmental or therapeutic conditions. Recognizing mid-range inhomogeneity helps researchers interpret microscopy and spatial profiling data, design representative sampling strategies, and build more accurate models of tissue organization, development, disease progression, and treatment response.

Mid-range Inhomogeneity - Related Videos

Education

JoVE Business - Microeconomics

Ed through Mid-point Method

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2024

At point A, the price is $6 for 120 units. Moving to point B, the price increases to $9, resulting in a decrease in quantity demanded to 80 units. This translates to a 50 percent increase in price and a 33.33 percent decrease in quantity, leading to a price elasticity value of 33.33/50 or 0.67. Conversely, moving from point B to A, entails a 33.33 percent decline in price and a 50 percent increase in quantity. This yields a price elasticity of 50/33.33 or 1.5. This discrepancy arises from the...

Range

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2023

The range is one of the measures of variation. It can be defined as the difference between a dataset's highest and lowest values. For example, in the study of seven 16-ounce soda cans, the filled volume of soda was measured, thus producing the following amount (in ounces) of soda: 15.9; 16.1; 15.2; 14.8; 15.8; 15.9; 16.0; 15.5 Measurements of the amount of soda in a 16-ounce can vary since different subjects record these measurements or since the exact amount - 16 ounces of liquid, was not...

Research

JoVE Journal - Engineering

In-situ Tapering of Chalcogenide Fiber for Mid-infrared Supercontinuum Generation

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Cited by 5 •

2013

We describe a method for in-situ tapering of As2S3 fibers to achieve efficient mid-infrared supercontinuum generation. By tapering while monitoring the supercontinuum’s spectrum, the spectral width can be maximized for a fiber taper. In-situ fiber tapering can be applied to optimize the performance of other fiber-based devices.

¹H NMR: Long-Range Coupling

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2024

The coupling interactions of nuclei across four or more bonds are usually weak, with J values less than 1 Hz. While these are usually not observed in spectra, the presence of multiple bonds along the coupling pathway can result in observable long-range coupling. In alkenes, spin information is communicated via σ–π overlap, as seen in allylic (four-bond) and homoallylic (five-bond) couplings. These coupling interactions are stronger when the σ bond is parallel to the alkene π orbitals.

The Utility of Stage-specific Mid-to-late Drosophila Follicle Isolation

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Cited by 12 •

2013

Stage-specific isolation of mid-to-late Drosophila follicles is useful for a variety of purposes. Such follicles develop in culture, which allows for genetic and/or pharmacologic manipulations to be coupled with in vitro development assays and live imaging. Additionally, follicles can be used for molecular studies, such as isolating mRNA and protein.

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