Organelle Fission

Organelle fission is the process by which a membrane-bound organelle divides into two or more daughter compartments, enabling organelle maintenance, distribution, and adaptation within cells. It typically involves recruitment of membrane-remodeling proteins to a division site, followed by membrane constriction and scission; in mitochondria, the dynamin-related protein Drp1 assembles around the outer membrane and uses GTP hydrolysis to promote division. Fission supports mitochondrial quality control, organelle inheritance, and cell proliferation, while abnormal regulation can alter cellular metabolism and contribute to disease. Studying this process helps clarify how cells organize internal compartments and maintain functional organelle populations.

Organelle Fission - Related Videos

Education

JoVE Core - Chemistry

Nuclear Fission

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2020

Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large number of different...

Research

JoVE Journal - Biology

Spatiotemporal Analysis of Cytokinetic Events in Fission Yeast

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Cited by 6 •

2017

The fission yeast, Schizosaccharomyces pombe is an excellent model system to study cytokinesis, the final stage in cell division. Here we describe a microscopy approach to analyze different cytokinetic events in live fission yeast cells.

Microscopy of Fission Yeast Sexual Lifecycle

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Cited by 38 •

2016

We provide a reproducible basic method for the long-term microscopy of the fission yeast sexual lifecycle. With minor adjustments described, the presented protocol allows research focus on different steps of the reproductive process.

Binary Fission

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2026

Fission is the division of a single entity into two or more parts, which regenerate into separate entities that resemble the original. Organisms in the Archaea and Bacteria domains reproduce using binary fission, in which a parent cell splits into two parts that can each grow to the size of the original parent cell. This asexual method of reproduction produces cells that are all genetically identical. The speed of Bacterial Fission Though its speed varies among species, binary fission is...

Binary Fission

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2025

Binary fission is the primary mode of asexual reproduction in prokaryotes, such as bacteria. It results in the production of two genetically identical daughter cells. This highly efficient process ensures the rapid propagation of bacterial populations under favorable conditions and involves coordinated cellular and molecular events.DNA Replication and SeparationThe process begins with the replication of the bacterial chromosome. The circular DNA molecule unwinds at a specific origin of...

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