Roswell Park Memorial Institute
Roswell Park Memorial Institute - Related Videos
01:29
Institutional Markets
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2025
Organizations in healthcare, education, and government sectors typically make large-scale purchases and have specific buying needs driven by various regulations, standards, and long-term objectives. Understanding the characteristics and behaviors of institutional buyers is crucial for marketers aiming to engage with this segment effectively. Characteristics of Institutional Markets Institutional markets are characterized by their size and purchasing power. Institutions often procure goods and...
01:25
Institutional Investors
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2026
Institutional investors play a significant role in financial markets due to the large volume of assets they manage. These include pension funds, mutual funds, insurance companies, and hedge funds. Behavioral finance, which studies how psychological factors influence financial decisions, offers unique insights into their behavior and decision-making processes.While institutional investors are generally perceived as rational and well-informed, they are not immune to behavioral biases. Herding...
09:13
A Real-world What-Where-When Memory Test
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Cited by 3 •
2017
The Real-World What-Where-When memory test is a novel episodic memory test, in which participants need to recall which objects have been hidden in which locations on which of two distinct occasions. It is easy to run and is sensitive to normal cognitive aging.
08:06
Eye Movement Monitoring of Memory
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Cited by 10 •
2010
Eye movement monitoring (or eye tracking) reveals where in space the eyes linger, when and for how long. Here, we demonstrate how eye tracking can be used to investigate the integrity of memory in multiple participant populations, without requiring verbal, or otherwise explicit, reports.
10:06
An Introduction to Learning and Memory
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2023
Learning is the process of acquiring new information and memory is the retention or storage of that information. Different types of learning, such as non-associative and associative learning, and different types of memory, such as long-term and short-term memory, have been associated with human behaviors. Studying these components in detail helps behavioral scientists understand the neural mechanisms behind these two complex phenomena. JoVE's overview on learning and memory introduces common...
FAQs
Amino acids provide building materials for cellular processes, while glucose supplies a metabolic energy source. Vitamins support biochemical reactions, and inorganic salts help maintain osmotic balance, which affects cell integrity. Buffering components help stabilize pH during culture. Together, these formulation elements create chemical conditions that support cell viability and sustained activity in controlled laboratory experiments.
The basal formulation does not meet every cell type’s nutritional and growth requirements. Researchers therefore add serum or other supplements when needed to provide additional support for particular cells. This adjustment is especially relevant when maintaining lymphocytes, leukocytes, hybridomas, or other suspension cultures, because their responses and viability can depend on the selected supplementation strategy.
Small differences in preparation or culture conditions can alter pH, osmotic balance, nutrient availability, and overall cell viability. Consistent preparation reduces variation between experiments, while controlled environmental conditions help cells remain in a stable physiological setting. These practices are important for reproducibility, particularly when researchers compare cell behavior, immune responses, or drug-related effects across samples.
Researchers should prepare the medium consistently, select supplements according to the cultured cell’s requirements, and maintain controlled environmental conditions throughout the experiment. The culture system must preserve nutrient availability, osmotic balance, and a suitable pH rather than relying on the basal formulation alone. Careful control of these factors helps maintain viable cells and produces more interpretable results.
RPMI 1640 is particularly useful in immunology, hematology, cancer biology, and drug-response studies. Its use with lymphocytes, leukocytes, hybridomas, and other suspension cells supports experiments involving immune-cell maintenance, blood-related cell biology, tumor research, and treatment-response assessment. The medium therefore connects routine cell culture with broader investigations of mammalian cellular behavior.
Cultures maintained under consistent RPMI conditions can support evaluation of cell viability, cellular responses, and responses to experimental drugs. In immunology and hematology, researchers may examine how lymphocytes or leukocytes behave under defined culture conditions; in cancer biology, the same system can support drug-response studies. Reliable maintenance improves confidence that observed differences reflect the experiment rather than inconsistent culture conditions.