Tissue Manipulation
Tissue Manipulation - Related Videos
13:27
Osteopathic Manipulative Treatment as a Useful Adjunctive Tool for Pneumonia
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Cited by 50 •
2014
Pneumonia is one of the top ten leading causes of death in the U.S. Osteopathic manipulative techniques (OMT) may be utilized as an adjunctive therapy in the treatment of pneumonia to enhance biomechanical and immune function; and ultimately, to reduce hospital stay, duration of antibiotics, incidence of respiratory failure, and mortality. In this video-article, we will review randomized controlled studies on the use of OMT in pneumonia patients, as well as demonstrate specific hands-on...
05:56
Manipulating the Murine Lacrimal Gland
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Cited by 15 •
2014
The lacrimal gland (LG) is a branching organ that produces the aqueous components of tears necessary for maintaining vision and ocular health. Here we describe murine LG dissection and ex vivo culture techniques to decipher signaling pathways involved in LG development.
07:49
Rod-based Fabrication of Customizable Soft Robotic Pneumatic Gripper Devices for Delicate Tissue Manipulation
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Cited by 10 •
2016
This protocol describes a rod-based approach, combining 3D-printing and soft lithography techniques for fabricating the soft gripper devices. This approach eliminates the need for an external air source by incorporating a chamber component and reduces the chance of occlusion during the sealing process, particularly for miniaturized pneumatic channels.
08:18
Visualizing Motion Patterns in Acupuncture Manipulation
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Cited by 6 •
2016
Here, we present a protocol for using the Acupuncture Manipulation Education System (AMES) in the training of acupuncture manipulation skills using phantom acupoints.
05:08
Manipulating an Independent Variable through Embodiment
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2023
Source: Laboratories of Gary Lewandowski, Dave Strohmetz, and Natalie Ciarocco—Monmouth University In any experiment, the researcher attempts to manipulate participants in one group to have different thoughts, experiences, or feelings than the other groups in the study. Some manipulations are overt, while others can be quite subtle. Embodiment is a growing research area focused on the theory that subtle physical experiences can unconsciously influence a person’s thoughts. For example if a...
FAQs
Extracellular matrix (ECM) provides the supporting framework that helps maintain tissue structure while cells perform their activities. Manipulating this matrix alongside cells allows researchers to examine how structural organization relates to cellular behavior. This relationship is important when studying development, regeneration, disease mechanisms, or strategies for tissue repair.
Mechanical or enzymatic dissociation separates a tissue into a preparation in which cellular behavior can be examined more directly, whereas culture studies cells or tissue under defined conditions. Using these approaches for different purposes helps researchers distinguish effects associated with cell activity from those associated with tissue organization and structure.
Defined biochemical and physical conditions let researchers alter the environment surrounding manipulated tissue and observe resulting changes in cellular behavior or tissue organization. Because these conditions can be specified rather than left uncontrolled, they help connect an experimental treatment or physical setting with an observed biological response. This supports disease studies, therapy evaluation, and tissue-engineering research.
A study may begin with dissection to isolate a tissue, followed by mechanical or enzymatic dissociation, culture, transplantation, or treatment with selected biochemical and physical conditions. The procedure is not fixed; researchers choose and combine these steps according to whether they need to examine tissue structure, cellular activity, biological responses, or potential repair strategies.
Biologists use these approaches to investigate development, regeneration, and disease mechanisms, as well as to study tissue engineering. Manipulated tissues can provide models for examining biological processes and for testing how cells and tissue organization respond to controlled interventions. The resulting information can guide evaluation of potential therapies and approaches to damaged tissue.
In tissue engineering, researchers use controlled handling, culture, transplantation, or defined treatments to connect cellular behavior with tissue organization. These studies help evaluate strategies for repairing or replacing damaged tissues rather than examining cells in isolation. The central outcome is a better understanding of how biological structure and activity can be coordinated for regenerative purposes.