Ultrasonic Dissector

An ultrasonic dissector is a precision instrument that uses high-frequency mechanical vibrations to separate, cut, or disrupt biological tissue and other soft specimens. It matters because it can provide localized processing with less mechanical force than conventional cutting methods. In operation, a piezoelectric transducer converts electrical energy into rapid motion at an ultrasonic frequency; a vibrating tip transfers this energy to the sample, fragmenting material and supporting controlled dissection. In biology, ultrasonic dissection supports tissue isolation, specimen preparation, and cell or tissue disruption for microscopy, molecular analysis, and experimental workflows.

Ultrasonic Dissector - Related Videos

Research

JoVE Journal - Neuroscience
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Assessment of Ultrasonic Vocalizations During Drug Self-administration in Rats

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Cited by 17 •

2010

Drug self-administration and ultrasonic vocalizations (USV) are used as behavioral assessments in animal research, but rarely in combination. The purpose of this article is to describe the advantages of recording USVs during drug self-administration procedures to assess affective responses to drug experience.

Research

JoVE Journal - Neuroscience
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Targeted Training of Ultrasonic Vocalizations in Aged and Parkinsonian Rats

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Cited by 31 •

2011

Voice disorders are debilitating in aging and Parkinson disease. The ultrasonic vocalizations of rats, also affected by these conditions, can be used to study these voice disorders, their neural substrates, and the nature of functional recovery with behavioral intervention.

Research

JoVE Journal - Engineering

Experiments on Ultrasonic Lubrication Using a Piezoelectrically-assisted Tribometer and Optical Profilometer

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Cited by 3 •

2015

We present a protocol for using a piezoelectrically-assisted tribometer and optical profilometer to investigate the dependence of ultrasonic wear and friction reduction on linear velocity, contact pressure, and surface properties.

Determining Ultrasonic Vocalization Preferences in Mice using a Two-choice Playback Test

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Cited by 22 •

2015

Ultrasonic vocalizations (USVs) in mice differ depending on age, sex, condition, and genetic background. Using two ultrasound emitters broadcasting simultaneously in different locations, this two-choice test can evaluate murine recognition and preference responses to different characteristics of USVs.

Research

JoVE Journal - Behavior
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Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication

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Cited by 80 •

2016

Mouse ultrasonic vocalizations are used as proxies to model the genetic bases of vocal communication deficits in mouse models for neuropsychiatric disorders. The present protocol describes three experimental contexts that reliably elicit ultrasonic vocalizations from pups (throughout development) and adult mice (same-sex interactions, male-estrus female interactions).

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