Ultrasonic Elastography

Ultrasonic elastography is a noninvasive imaging technique that maps tissue stiffness, providing information beyond the structural detail of conventional ultrasound. It applies mechanical pressure or generates acoustic radiation force to produce tissue displacement and shear waves, then measures their propagation with ultrasound; faster wave movement generally indicates stiffer tissue. In biology and medicine, these stiffness maps help characterize organs, lesions, fibrosis, and other changes in tissue structure. The method supports research and clinical assessment while reducing reliance on invasive sampling, and its quantitative measurements can improve the study of disease progression and treatment response.

Ultrasonic Elastography - Related Videos

Research

JoVE Journal - Bioengineering

Magnetic Resonance Elastography Methodology for the Evaluation of Tissue Engineered Construct Growth

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Cited by 16 •

2012

The procedure demonstrates the methodology of magnetic resonance elastography for monitoring the engineered outcome of adipose and osteogenic tissue engineered constructs through noninvasive local assessment of the mechanical properties using microscopic magnetic resonance elastography (μMRE).

Magnetic Resonance Elastography for Assessing Viscoelastic Properties

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2025

Source: Feng, Y., et al. Viscoelastic Characterization of Soft Tissue-Mimicking Gelatin Phantoms using Indentation and Magnetic Resonance Elastography. J. Vis. Exp. (2022) This video demonstrates the method of magnetic resonance elastography (MRE) for assessing tissue viscoelastic properties by analyzing shear wave propagation through a gelatin phantom, mimicking brain tissue. The process involves generating and capturing shear waves with magnetic resonance imaging or MRI and analyzing wave...

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

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2025

The goal of this protocol is to showcase the technique and use of point-of-care transient elastography for pediatric gastroenterologists monitoring hepatobiliary involvement and advanced cystic fibrosis liver disease in persons with cystic fibrosis.

Anisotropic Polyvinyl Alcohol Phantom Fabrication for Ultrasound Elastography: Procedure and Quality Controls

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2026

This protocol describes a robust, reproducible method for fabricating anisotropic polyvinyl alcohol (PVA) phantoms—essential tools for validating ultrasound elastography techniques targeting mechanically anisotropic soft tissues (e.g., skeletal muscle).

Research

JoVE Journal - Neuroscience
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Assessment of Ultrasonic Vocalizations During Drug Self-administration in Rats

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Cited by 17 •

2010

Drug self-administration and ultrasonic vocalizations (USV) are used as behavioral assessments in animal research, but rarely in combination. The purpose of this article is to describe the advantages of recording USVs during drug self-administration procedures to assess affective responses to drug experience.

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