Saline Flush

A saline flush is the instillation of sterile sodium chloride solution, commonly 0.9% saline, into an intravenous catheter or vascular access device to maintain patency and support safe medication delivery. By gently injecting the solution, clinicians clear residual medication or blood from the lumen and generate positive pressure that helps limit backflow when the device is used correctly. Saline flushes are commonly performed before and after intravenous medications, infusions, or blood sampling, with technique and volume determined by the device and clinical protocol. Proper use helps confirm line function, reduce medication incompatibility, and support reliable vascular access in clinical care.

Saline Flush - Related Videos

Education

JoVE Science Education - Clinical Skills

Assessing and Flushing a Peripheral Intravenous Line

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2023

Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT After peripheral intravenous (IV) access is initiated, it is important to assess and maintain the IV catheter according to institutional policies and nursing standards of practice. The regular assessment of the insertion site and the surrounding areas for signs of complications is necessary to prevent IV catheter complications, including infiltration, phlebitis, infection, extravasation, or...

Research

JoVE EoE - Neuropathology

A Hypertonic Saline Injection Technique for Inducing Glaucoma in Rats

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2025

This video demonstrates glaucoma induction in an anesthetized rat by injecting hypertonic saline into the episcleral vein. The saline enters the trabecular meshwork via Schlemm's canal, causing tissue scarring, which blocks aqueous humor outflow and raises intraocular pressure. The elevated pressure damages retinal ganglion cells, leading to glaucoma.

Salinity Tolerance of Alishewanella Species Isolated from Seawall Muddy Water

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2025

Begin with a culture of Alishewanella, a Gram-negative, salt-tolerant bacterium.Next, streak the culture onto agar plates containing increasing concentrations of sodium chloride to simulate varying levels of saline stress.Overlay each plate with a layer of unsolidified medium to prevent oxygen diffusion and maintain the culture in an oxygen-limited environment.Seal and incubate the plates at an optimum temperature to support bacterial growth.During incubation, the bacterium exhibits varying...

Salinity-dependent Toxicity Assay of Silver Nanocolloids Using Medaka Eggs

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Cited by 2 •

2016

Embryonic stages are the most susceptible to xenobiotics. Although chemical toxicity depends on salinity, no method exists to test the salinity dependence of toxicity to aquatic organisms. Here, we describe a new and high-throughput method for determining the salinity dependence of toxicity to aquatic embryos.

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

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2024

Saline nasal lavage can be used to sample the canine nasal immune microenvironment. Because the approach is relatively non-invasive and does not disrupt the nasal tissues, it can be performed serially. Cells and proteins collected from the nasal lavage technique can be processed for various laboratory analyses.

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