Telangiectasias

Telangiectasias are small, permanently dilated superficial blood vessels that appear as fine red, purple, or branching lines on the skin or mucous membranes, making them important clinical signs as well as cosmetic findings. They develop when capillaries, arterioles, or venules near the tissue surface widen and remain enlarged; many blanch with pressure because blood can be displaced from these vessels. Telangiectasias may occur as isolated lesions or alongside sun exposure, aging, rosacea, connective tissue disorders, liver disease, medications, or inherited vascular syndromes. Clinical evaluation helps distinguish benign changes from findings that warrant investigation, while laser therapy, intense pulsed light, or sclerotherapy may reduce their appearance in selected cases.

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Research

JoVE Journal - Neuroscience
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High-throughput Analysis of Locomotor Behavior in the Drosophila Island Assay

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Cited by 10 •

2017

The island assay is a relatively new, cost-effective assay that can be used to evaluate the basic locomotor behavior of Drosophila melanogaster. This manuscript describes algorithms for automatic data processing and objective quantification of island assay data, making this assay a sensitive, high-throughput readout for large genetic or pharmacological screens.

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