Coil Embolization
Coil Embolization - Related Videos
05:52
Myocardial Infarction by Percutaneous Embolization Coil Deployment in a Swine Model
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Cited by 7 •
2021
Myocardial infarction (MI) animal models that emulate the natural process of the disease in humans are crucial to understanding pathophysiological mechanisms and testing the safety and efficacy of new emergent therapies. Here, we describe an MI swine model created by deploying a percutaneous embolization coil.
03:06
Combination of High Ligation and Intraoperative Embolization Using Polidocanol for Treatment of Varicoceles
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2023
To reduce the postoperative recurrence rate of varicocelectomy, we combined high ligation of varicocele with intraoperative embolization. We injected polidocanol from the spermatic vein during surgery to embolize the branches of the spermatic vein and collateral veins. This is an alternative surgical method for the treatment of varicocele.
11:14
Combining Wet and Dry Lab Techniques to Guide the Crystallization of Large Coiled-coil Containing Proteins
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Cited by 2 •
2017
We describe a framework incorporating straightforward biochemical and computational analysis to guide the characterization and crystallization of large coiled-coil domains. This framework can be adapted for globular proteins or extended to incorporate a variety of high-throughput techniques.
07:00
How to Use the H1 Deep Transcranial Magnetic Stimulation Coil for Conditions Other than Depression
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Cited by 13 •
2017
The H1 deep transcranial magnetic stimulation coil is FDA-cleared for the treatment of depression. We demonstrate how to utilize the H1 for other conditions, such as auditory hallucinations and PTSD, by moving the helmet to different locations over the subject's skull.
08:29
Microvascular Embolism Mouse Model for In Vivo Two-photon Microscopy Using Fluorescent Polystyrene Microspheres
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2025
This protocol contains a thorough description of a step-by-step approach for a chronic cranial window and microvascular embolism mouse model optimized for in vivo two-photon microscopy imaging using fluorescent polystyrene microspheres.
FAQs
Coil embolization achieves vessel closure through two linked effects: the released soft metal coils occupy space at the target and promote local blood clot formation. The resulting clot, together with the coil mass, produces an occlusion intended to persist over time. This mechanism allows treatment to isolate an intracranial aneurysm or another selected vascular lesion from circulation.
The clinical objective determines the target and desired vascular change. An aneurysm may be treated to prevent rupture, whereas internal bleeding calls for flow control. In selected vascular malformations or tumors, reducing blood flow is the aim. Thus, one coil-based mechanism can support different therapeutic outcomes depending on which lesion or vessel clinicians choose to occlude.
Instead of reaching a lesion through an open operation, clinicians guide a catheter through the vascular system and deploy coils from within the vessels under imaging. This endovascular route offers a targeted alternative to open surgery. Its clinical value lies in directing an occlusion toward a defined vascular site while using minimally invasive access.
Imaging provides the guidance needed to move the catheter through the vascular system and identify the target site for coil release. Because treatment depends on placing coils at a selected location, image-guided navigation connects the clinician’s access route with the intended vascular effect. This is especially relevant in neurovascular care, where intracranial aneurysms are common targets.
The procedure begins with catheter advancement through the vascular system under imaging. Once the catheter reaches the selected lesion or vessel, clinicians release soft metal coils at that location. The coils then encourage local clot formation and create the intended occlusion. This sequence links image-guided access, targeted deployment, and a localized vascular response.
Beyond aneurysm care, clinicians may apply coil embolization to control internal bleeding or reduce blood flow to selected vascular malformations and tumors. These uses show that the technique is not limited to preventing rupture. Its broader medical role is to create a deliberate, localized reduction or interruption of circulation when that vascular change supports treatment.