Intra-operative Guidance

Intra-operative guidance refers to the use of real-time information and tools during surgery to help clinicians localize anatomy, assess tissue, and make precise decisions. It combines approaches such as surgical navigation, intra-operative imaging, anatomical landmarks, and physiological monitoring, which provide feedback as the procedure progresses and help account for changes in tissue position or condition. In medicine, these methods can improve the accuracy of tissue targeting, support minimally invasive procedures, and help surgeons avoid critical structures. Their continued development may strengthen surgical planning, procedural safety, and personalized treatment across specialties.

Intra-operative Guidance - Related Videos

Research

JoVE Journal - Medicine

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion

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Cited by 10 •

2019

The purpose of this article is to provide image-guidance for minimally invasive transforaminal interbody fusion.

Research

JoVE Journal - Medicine
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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

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Cited by 41 •

2010

Fluorescence imaging is a promising innovative modality for image-guided surgery in surgical oncology. In this video we describe the technical procedure for detection of the sentinel lymph node using fluorescence imaging as showcased in gynecologic oncologicy. A multispectral fluorescence camera system, together with the fluorescent agent indocyanine green, is applied.

Intraoperative Gastroscopy for Tumor Localization in Laparoscopic Surgery for Gastric Adenocarcinoma

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Cited by 12 •

2016

In early gastric cancer, the aim of surgery is to precisely remove the distal stomach including the primary tumor. To do this, accurate localization of the tumor is crucial, especially in totally laparoscopic surgery. This protocol describes a procedure for intraoperative gastroscopy in totally laparoscopic subtotal gastrectomy.

Automated Robotic Dispensing Technique for Surface Guidance and Bioprinting of Cells

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Cited by 9 •

2016

This protocol describes a bioprinting methodology using an automated robotic depositing system that incorporates etched topographical guidance cues with the precision deposition of a cell bearing hydrogel bioink. The printed cells are directly delivered to the etched features and are able to sense and orientate with them.

Use of pHluorin to Assess the Dynamics of Axon Guidance Receptors in Cell Culture and in the Chick Embryo

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Cited by 10 •

2014

We describe here the use of a pH-sensitive green fluorescent protein variant, pHluorin, to study the spatio-temporal dynamics of axon guidance receptors trafficking at the cell surface. The pHluorin-tagged receptor is expressed both in cell culture and in vivo, using electroporation of the chick embryo.

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