Pancreaticoduodenectomy

Pancreaticoduodenectomy, commonly called the Whipple procedure, is a complex operation that removes the pancreatic head and nearby structures to treat selected diseases of the pancreas, bile duct, and duodenum. Surgeons typically resect the pancreatic head, duodenum, gallbladder, and part of the bile duct, then restore gastrointestinal continuity by connecting the remaining pancreas, bile duct, and stomach or intestine to the small bowel. Most often used for resectable pancreatic or periampullary cancers, the procedure can provide the possibility of long-term disease control, but it requires careful patient selection and management of risks such as pancreatic fistula, delayed gastric emptying, and infection.

Pancreaticoduodenectomy - Related Videos

Research

JoVE Journal - Cancer Research
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Application of Simplified Stent-bridging Pancreaticogastrostomy in Open Pancreaticoduodenectomy

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2026

Here, we present the stent-bridging pancreaticogastrostomy (PG) technique, which uses a stent to bridge the remnant pancreas to the stomach during open pancreaticoduodenectomy. The stent-bridging PG aims to simplify the anastomosis, achieve complete diversion of pancreatic juice, and minimize manipulation of the pancreatic remnant.

Research

JoVE Journal - Medicine

Technical Detail for Robot Assisted Pancreaticoduodenectomy

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Cited by 8 •

2019

The following manuscript details a stepwise approach to the robot-assisted pancreaticoduodenectomy performed at the University of Pittsburgh Medical Center.

Modified Single-Loop Reconstruction for Pancreaticoduodenectomy

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Cited by 2 •

2019

The technique of modified single-loop reconstruction following pancreaticoduodenectomy separates pancreatic secretion from bile, thus reducing the severity of POPF without prolonging the duration of surgery.

Management of the Uncinate Process in No-Touch Laparoscopic Pancreaticoduodenectomy

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Cited by 2 •

2023

Complete resection of the uncinate process and mesopancreas is one of the most important and difficult processes in laparoscopic pancreatoduodenectomy (LPD). This article presents a method for managing the uncinate process in no-touch LPD using the median-anterior and left-posterior approaches to the superior mesenteric artery (SMA).

Reverse Needle Continuous Suture of the Pancreatic Duct to Jejunal Mucosal Pancreaticointestinal Anastomosis in Laparoscopic Pancreaticoduodenectomy

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2025

To circumvent the difficulty in completing the anastomosis of the pancreatic duct and jejunal mucosa under laparoscopy for patients with a small pancreatic duct and soft and fragile pancreatic tissue, we introduce a reverse needle continuous suture technique for laparoscopic pancreaticojejunostomy of the pancreatic duct and jejunal mucosa.

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