Research Aquarium
Research Aquarium - Related Videos
08:04
Cytotoxic Efficacy of Photodynamic Therapy in Osteosarcoma Cells In Vitro
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Cited by 8 •
2014
The protocol reported here allows the evaluation of the efficacy of photodynamic therapy (PDT) in cell lines and the optimization of the PDT settings before applying the therapy in animal models.
06:20
A Simple Approach to Manipulate Dissolved Oxygen for Animal Behavior Observations
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Cited by 1 •
2016
This article describes a simple and reproducible protocol to manipulate dissolved oxygen conditions in a laboratory setting for animal behavior studies. This protocol may be used in both teaching and research laboratory settings to evaluate organismal response of macroinvertebrates, fishes, or amphibians to changes in dissolved oxygen concentration.
05:40
Comparison of Scale in a Photosynthetic Reactor System for Algal Remediation of Wastewater
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Cited by 3 •
2017
An experimental methodology is presented to compare the performance of small (100 L) and large (1,000 L) scale reactors designed for algae remediation of landfill wastewater. System characteristics, including surface area to volume ratio, retention time, biomass density, and wastewater feed concentrations, can be adjusted based on application.
09:31
Effective Techniques for the Feeding and Ex Situ Culture of a Brooding Scleractinian Coral, Pocillopora acuta
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Cited by 2 •
2023
Climate change is impacting coral reef ecosystems globally. Corals sourced from ex situ aquaculture systems can help support restoration and research efforts. Herein, feeding and coral culture techniques that can be used to promote the long-term maintenance of brooding scleractinian corals ex situ are outlined.
12:24
Laboratory Estimation of Net Trophic Transfer Efficiencies of PCB Congeners to Lake Trout (Salvelinus namaycush) from Its Prey
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Cited by 1 •
2014
A technique for laboratory estimation of net trophic transfer efficiency of polychlorinated biphenyl (PCB) congeners to piscivorous fish from their prey is presented. To maximize applicability of the laboratory results to the field, the piscivorous fish should be fed prey fish that are typically eaten in the field.
FAQs
Continuous filtration and aeration help keep water conditions suitable for housed organisms, while monitoring temperature, pH, dissolved oxygen, and waste provides information about system status. This combination supports animal health and limits environmental variation, so observations are more likely to reflect the experimental factors rather than uncontrolled changes in the aquatic environment.
Consistent water quality reduces environmental variation that could otherwise affect animal health or experimental observations. Monitoring temperature, pH, dissolved oxygen, and waste gives the facility defined conditions for comparing results. When those conditions remain standardized, findings can be assessed in relation to the intended disease, toxicology, drug-response, or regeneration study rather than uncertain changes in the aquatic environment.
Zebrafish and other aquatic model species support medical research across several levels of biology. In a research aquarium, investigators can examine development and genetics, model disease mechanisms, assess toxicology and drug responses, and observe tissue regeneration. These studies may reveal biological pathways or therapeutic effects relevant to human health.
Preparation begins with housing the selected organisms under controlled laboratory conditions. The recirculating system must filter and aerate the water, while the facility monitors temperature, pH, dissolved oxygen, and waste. Animal care, breeding when needed, and experimental observation then proceed within these standardized conditions to support health and reproducible results.
Medical researchers can use these facilities to investigate development, genetics, disease mechanisms, toxicology, drug responses, and tissue regeneration. The range is important because the same controlled setting supports both fundamental biological studies and investigations of effects relevant to human health, including observed therapeutic effects.
Observations from aquatic models can contribute to medical research by identifying biological pathways or therapeutic effects relevant to human health. Their value comes from linking controlled animal studies with questions about disease mechanisms, drug responses, toxicology, development, genetics, and tissue regeneration. The resulting evidence helps characterize how biological processes or treatments behave in the studied models.