Retroperitoneal Lesion
Retroperitoneal Lesion - Related Videos
07:25
Ovine Lumbar Intervertebral Disc Degeneration Model Utilizing a Lateral Retroperitoneal Drill Bit Injury
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Cited by 18 •
2017
Intervertebral disc degeneration is a significant contributor to back pain and a leading cause of disability worldwide. Numerous animal models of intervertebral disc degeneration exist. We demonstrate an ovine model of intervertebral disc degeneration, utilizing a drill bit, which achieves a consistent disc injury and reproducible level of disc degeneration.
03:42
Retroperitoneal Laparoscopic Debridement and Drainage for Pancreatic Abscess
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Cited by 1 •
2024
To improve the drainage of patients with necrotizing pancreatitis complicated with peripancreatic abscess and reduce the mortality of patients with necrotizing pancreatitis, we adopted a retroperitoneal approach for peripancreatic abscess debridement and drainage by laparoscopy.
09:22
Sectioning Mammary Gland Whole Mounts for Lesion Identification
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Cited by 13 •
2017
We developed a method to successfully remove, process, section, and stain, for histopathological evaluation, mammary tissue that had originally been fixed on slides as whole mounts. This method may promote the collection and evaluation of mammary gland whole mounts in reproductive and developmental test guideline studies.
08:16
Comparative Lesions Analysis Through a Targeted Sequencing Approach
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2019
This article describes a method to identify clonal and subclonal alterations among different specimens from a given patient. Although the experiments described here focus on a specific tumor type, the approach is broadly applicable to other solid tumors.
05:51
A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
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Cited by 13 •
2014
Atherosclerosis is a chronic inflammatory process. This manuscript illustrates an easy to use ex vivo model to investigate fresh carotid or coronary artery plaques. The ex vivo model allows for the investigation of potential substances on the inflammatory milieu in human atherosclerotic lesions and results can be analyzed by various methods.
FAQs
Because the retroperitoneum lies behind the peritoneal cavity, a lesion can enlarge before it becomes clinically apparent. Symptoms may emerge only when growth, inflammation, bleeding, or compression affects nearby organs. This delayed presentation matters clinically because the eventual mass may have a complex relationship with surrounding structures, making both interpretation and treatment planning more demanding.
A retroperitoneal lesion may arise from an organ, lymphatic or vascular structure, nerve, connective tissue, or metastatic disease. These possibilities indicate that similar-appearing masses can represent biologically different processes. Establishing the likely origin therefore helps clinicians interpret the lesion’s composition, anticipate its anatomic relationships, and select appropriate diagnostic and management strategies.
Symptoms reflect what the lesion does locally, not simply its size or label. Growth can compress adjacent organs, while inflammation or bleeding can create additional clinical effects. A lesion may also represent metastatic disease rather than a process originating in the retroperitoneum. Linking symptoms to these mechanisms helps clinicians interpret the mass in the context of its possible origin.
Contrast-enhanced CT or MRI helps characterize a retroperitoneal lesion by showing its origin, composition, and relationship to major vessels and nearby structures. These details provide more than a simple confirmation that a mass is present. They support assessment of whether the lesion can be adequately sampled, monitored, or approached during treatment planning.
Image-guided biopsy is considered when tissue characterization is needed after clinical and imaging assessment. Using imaging to guide sampling helps target the lesion while accounting for its deep location and relationship to nearby structures. The resulting tissue information can help distinguish benign from malignant disease and determine whether surveillance, surgery, systemic therapy, or another specialized treatment is appropriate.
Accurate characterization connects the lesion’s appearance and tissue origin with the next clinical decision. Findings may support surveillance for a lesion requiring observation, surgery for a resectable process, systemic therapy for disease needing medical treatment, or another specialized approach. This decision-making framework is especially important when the lesion is near major vessels or adjacent organs.