Saline Purge

Saline purge is a medical method that uses a saline solution to stimulate rapid evacuation of intestinal contents, making it relevant to bowel cleansing and selected gastrointestinal treatments. When consumed or administered under clinical supervision, dissolved salts increase the osmotic concentration within the intestinal lumen, drawing water into the bowel and promoting watery stool. This process can help clear the gastrointestinal tract before certain diagnostic or therapeutic procedures and may support carefully selected poisoning-management protocols. Because excessive fluid and electrolyte loss can cause dehydration or electrolyte imbalance, saline purge requires appropriate patient selection, dosing, and medical oversight.

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Research

JoVE Journal - Environment

Biofilm Removal Using Carbon Dioxide Aerosols without Nitrogen Purge

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Cited by 2 •

2016

Biofilms on surfaces can be effectively and rapidly removed by using a periodic jet of carbon dioxide aerosols without a nitrogen purge.

A Hypertonic Saline Injection Technique for Inducing Glaucoma in Rats

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2025

This video demonstrates glaucoma induction in an anesthetized rat by injecting hypertonic saline into the episcleral vein. The saline enters the trabecular meshwork via Schlemm's canal, causing tissue scarring, which blocks aqueous humor outflow and raises intraocular pressure. The elevated pressure damages retinal ganglion cells, leading to glaucoma.

Salinity Tolerance of Alishewanella Species Isolated from Seawall Muddy Water

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2025

Begin with a culture of Alishewanella, a Gram-negative, salt-tolerant bacterium.Next, streak the culture onto agar plates containing increasing concentrations of sodium chloride to simulate varying levels of saline stress.Overlay each plate with a layer of unsolidified medium to prevent oxygen diffusion and maintain the culture in an oxygen-limited environment.Seal and incubate the plates at an optimum temperature to support bacterial growth.During incubation, the bacterium exhibits varying...

Salinity-dependent Toxicity Assay of Silver Nanocolloids Using Medaka Eggs

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Cited by 2 •

2016

Embryonic stages are the most susceptible to xenobiotics. Although chemical toxicity depends on salinity, no method exists to test the salinity dependence of toxicity to aquatic organisms. Here, we describe a new and high-throughput method for determining the salinity dependence of toxicity to aquatic embryos.

Saline Lavage for Sampling of the Canine Nasal Immune Microenvironment

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2024

Saline nasal lavage can be used to sample the canine nasal immune microenvironment. Because the approach is relatively non-invasive and does not disrupt the nasal tissues, it can be performed serially. Cells and proteins collected from the nasal lavage technique can be processed for various laboratory analyses.

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