Sex Hormone Effects

Sex hormone effects are the physiological changes produced by estrogens, progestogens, and androgens throughout the body, shaping reproduction as well as tissues such as bone, muscle, and the brain. These hormones act mainly by binding intracellular or cell-surface receptors, altering gene transcription and cellular signaling in ways that depend on hormone concentration, receptor distribution, and life stage. In medicine, understanding these effects supports evaluation of puberty, fertility, menstrual and menopausal symptoms, endocrine disorders, and hormone therapies. Studying sex hormone effects also helps clinicians anticipate treatment benefits, adverse effects, and differences in disease risk across biological contexts.

Sex Hormone Effects - Related Videos

Research

JoVE Journal - Biology

Sex Hormone Detection In Human Tear Film Using Enzyme-Linked Immunosorbent Assays

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2026

This protocol describes an optimized enzyme-linked immunosorbent assay (ELISA) method to detect and quantify 17β-estradiol and testosterone in human tear fluid collected via microcapillary tubes. This approach enables minimally invasive measurement of tear hormone levels.

Murine Orchiectomy and Ovariectomy to Reduce Sex Hormone Production

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Cited by 12 •

2023

This manuscript describes a consistent way to quickly perform survival rodent orchiectomies and ovariectomies.

Education

JoVE Core - Biology

Types of Hormones

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2019

Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells. Steroid hormones are derived from cholesterol and are lipophilic in nature. This allows them to readily traverse the lipid-rich cell membrane to bind to their intracellular receptors in the cytoplasm or nucleus. Once bound, the cytoplasmic hormone-receptor complex translocates to the nucleus.

Plant Hormones

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2020

Plant hormones—or phytohormones—are chemical molecules that modulate one or more physiological processes of a plant. In animals, hormones are often produced in specific glands and circulated via the circulatory system. However, plants lack hormone-producing glands. Instead, plant hormones are often produced in regions of active growth, like the tips of roots and shoots. Additionally, even very low concentrations of plant hormones can have a profound effect on growth and development processes.

Hormonal Regulation

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2019

The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.

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