Military Brain Trauma
Military Brain Trauma - Related Videos
11:14
Acute Brain Trauma in Mice Followed By Longitudinal Two-photon Imaging
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Cited by 11 •
2014
Acute brain trauma is a severe injury that has no adequate treatment to date. Multiphoton microscopy allows studying longitudinally the process of acute brain trauma development and probing therapeutical strategies in rodents. Two models of acute brain trauma studied with in vivo two-photon imaging of brain are demonstrated in this protocol.
10:08
Pseudofracture: An Acute Peripheral Tissue Trauma Model
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Cited by 38 •
2011
Pseudofracture, a reproducible murine model of sterile musculoskeletal trauma, allows for evaluation of late term post-traumatic immune responses. This article describes the procedural execution of the model step by step, including the potential for experimental model combinations to permit study of multiple trauma.
07:01
Direct Mouse Trauma/Burn Model of Heterotopic Ossification
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Cited by 68 •
2015
An Achilles tenotomy and burn injury model of heterotopic ossification allows for the reliable study of trauma induced ectopic bone formation without the application of exogenous factors.
07:18
Focused Assessment with Sonography for Trauma (FAST) Exam: Image Acquisition
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Cited by 7 •
2023
The Focused Assessment with Sonography for Trauma (FAST) exam is a diagnostic point-of-care ultrasound examination used to screen for the presence of free fluid in the pericardium and peritoneum. Indications, techniques, and pitfalls of the procedure are discussed in this article.
09:55
Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
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Cited by 6 •
2018
We present a protocol of personalized script-driven trauma-related imagery and clinical assessments within a comparison design for investigating peritraumatic dissociation (PD), psychophysiological reactions, i.e. heart rate (HR) and skin conductance (SC), and psychological features of often severely traumatized individuals with borderline personality disorder (BPD).
FAQs
Military brain trauma can involve different physical forces, and each may place neural tissue under a different type of stress. Blast waves, blunt-force impacts, and rapid acceleration or deceleration are distinct exposure mechanisms. Comparing them helps neuroscience researchers relate the initiating event to disruption of neural tissue, blood vessels, and brain signaling, rather than treating every injury as biologically identical.
Inflammation matters because it can extend the effects of the initial physical insult. After neural tissue, blood vessels, or signaling systems are disrupted, secondary inflammatory responses may prolong cellular damage. This distinction separates the immediate mechanical injury from later biological processes, giving researchers a basis for studying why symptoms or impairment can continue beyond the original exposure.
The affected neural systems help shape the resulting clinical picture. Disruption in brain signaling can be examined alongside changes in cognition, behavior, or sensation, while damage to tissue or blood vessels may contribute to broader effects on brain function. Linking injury mechanism with these symptom domains allows neuroscience research to investigate recovery and persistent impairment in a structured way.
Assessment and monitoring are important because the consequences may change over time or remain persistent. Neuroscience approaches can examine cognition, behavior, sensation, and long-term brain health while relating findings to the suspected injury mechanism. Diagnostic approaches help characterize the effects, and clinical monitoring provides information about recovery or continuing impairment in service members and veterans.
Protective equipment is one practical application of this research. When investigators understand how blast waves, blunt impacts, or acceleration and deceleration can disrupt neural tissue and signaling, those mechanisms can inform efforts to improve protection during armed conflict, training, or service. The goal is to connect protection priorities with observed neurological consequences and the types of forces involved.
Rehabilitation strategies address the functional consequences identified after injury. Because military brain trauma may affect cognition, behavior, sensation, and long-term brain health, rehabilitation research can focus on impairments observed in a particular service member rather than relying only on exposure history. Clinical follow-up also supports continued evaluation of recovery and persistent impairment among service members and veterans.