Intravenous Infusion
Intravenous Infusion - Related Videos
08:32
Preparing and Administering Intermittent Intravenous Medications with an Infusion Pump
0 Views •
2017
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT Primary intermittent intravenous (IV) infusions are delivered alone as volume-controlled infusions, while secondary infusions are delivered with another IV fluid, usually maintenance fluids. Intermittent infusions are delivered over a specific amount of time, which is dictated by the type of medication, such as IV antibiotics. High-volume IV medications, anywhere from 50- to 500-mL...
07:22
Discontinuing Intravenous Fluids and a Peripheral Intravenous Line
0 Views •
2023
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT Intravenous (IV) fluid administration and peripheral IV catheters (PIVs) may be discontinued for a number of reasons. The most common reason for discontinuing IV fluids is that the patient has returned to normal body fluid volume (euvolemia) and is able to maintain adequate oral fluid intake or is being discharged from the hospital. In addition, the Centers for Disease Control Guidelines...
11:39
Peripheral Intravenous Catheter Insertion
0 Views •
2023
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT The purpose of peripheral intravenous catheter (PIV) insertion is to infuse medications, perform intravenous (IV) fluid therapy, or inject radioactive tracers for special examination procedures. Placing a PIV is an invasive procedure and requires the use of an aseptic, no-touch technique. Common IV venipuncture sites are the arms and hands in adults and the feet in children. According to...
07:08
Assessing and Flushing a Peripheral Intravenous Line
0 Views •
2023
Source: Madeline Lassche, MSNEd, RN and Katie Baraki, MSN, RN, College of Nursing, University of Utah, UT After peripheral intravenous (IV) access is initiated, it is important to assess and maintain the IV catheter according to institutional policies and nursing standards of practice. The regular assessment of the insertion site and the surrounding areas for signs of complications is necessary to prevent IV catheter complications, including infiltration, phlebitis, infection, extravasation, or...
12:09
Methods for Intravenous Self Administration in a Mouse Model
0 Views •
Cited by 35 •
2012
The intravenous self-administration (IVSA) paradigm is considered to be the gold standard in examining the reinforcing properties of drugs of abuse in rodents. This manuscript outlines the experimental procedures and surgical techniques necessary to obtain reliable IVSA data. In particular, meticulous catheter implantation and maintenance are highlighted.
FAQs
These variables determine how much drug enters the bloodstream and how quickly it arrives. Increasing the dose raises the total amount delivered, while changing concentration alters the volume required for administration. Extending or shortening infusion time changes the delivery rate, so pharmacologists consider all three when evaluating plasma exposure and treatment response.
The prescribed rate controls the pace at which a medication enters systemic circulation. A controlled rate can support more consistent drug exposure than irregular delivery, which is important when researchers or clinicians seek to maintain plasma concentrations over time. Rate selection therefore connects the administration plan with the intended pharmacologic response.
Vascular access affects whether the administered solution reaches the bloodstream as intended. Problems at the access site can alter delivery and contribute to complications such as infiltration, in which fluid enters surrounding tissue rather than remaining within the vessel. Assessing access is therefore part of protecting dose accuracy and reducing administration-related harm.
Because the gastrointestinal tract is bypassed, intravenous delivery does not depend on gastrointestinal absorption before the agent reaches systemic circulation. This supports rapid and reliable availability, which can be valuable for medicines requiring prompt action or dependable exposure. The distinction also makes infusion useful for pharmacokinetic evaluation of controlled systemic dosing.
A basic workflow includes selecting the prescribed solution and dose, establishing suitable vascular access, connecting the infusion device, and setting the ordered delivery rate. The operator then considers concentration and infusion time while observing for dosing problems, infiltration, or adverse reactions. These steps link the written regimen to actual systemic exposure.
This approach is useful when a therapy requires rapid systemic availability, reliable delivery, or controlled administration over time. Pharmacology applications include continuous drug delivery, maintenance of plasma concentrations, fluid replacement, and administration of medicines that may not be suited to gastrointestinal absorption. The choice depends on the intended response and dosing requirements.
Infusion studies allow investigators to examine how dose, concentration, infusion time, and delivery rate affect drug exposure and response. They can also support pharmacokinetic evaluation by relating the administration regimen to plasma concentrations over time. These observations help researchers assess controlled dosing strategies and interpret differences in therapeutic effect.
Monitoring should address dosing errors, infiltration, and adverse reactions because each can compromise safety or the intended treatment outcome. Incorrect dose, concentration, or rate may change systemic exposure, while access-site problems can interfere with delivery. Recognizing these issues helps pharmacology teams connect observed responses with the administration process and adjust care appropriately.